SOCS-6 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-82348

Novus Biologicals, part of Bio-Techne
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NBP2-82348-0.1ml
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit

Concentration

0.5 mg/ml

View all SOCS-6 Antibodies »

Product Summary for SOCS-6 Antibody

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of Human SOCS-6. Peptide sequence: GKDMASCDINGEDEKGGKNRSKSESLMGTLKRRLSAKQKSKGKAGTPSGS The peptide sequence for this immunogen was taken from within the described region.

Clonality

Polyclonal

Host

Rabbit

Theoretical MW

60 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for SOCS-6 Antibody

Western Blot: SOCS-6 Antibody [NBP2-82348]

Western Blot: SOCS-6 Antibody [NBP2-82348]

Western Blot: SOCS-6 Antibody [NBP2-82348] - Host: Rabbit. Target Name: SOCS6. Sample Tissue: Human U937 Whole Cell lysates. Antibody Dilution: 1ug/ml

Applications for SOCS-6 Antibody

Application
Recommended Usage

Western Blot

1.0 ug/ml
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, 2% Sucrose

Preservative

0.09% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: SOCS-6

SOCS6 is encoded by this gene contains a SH2 domain and a CIS homolog domain. The protein thus belongs to the cytokine-induced STAT inhibitor (CIS), also known as suppressor of cytokine signaling (SOCS) or STAT-induced STAT inhibitor (SSI), protein family. CIS family members are known to be cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by GM-CSF and EPO in hematopoietic cells. A high expression level of this gene was found in factor-independent chronic myelogenous leukemia (CML) and erythroleukemia (HEL) cell lines.

Long Name

Suppressor Of Cytokine Signaling 6

Alternate Names

HSPC060, SOCS6

Gene Symbol

SOCS6

Additional SOCS-6 Products

Product Documents for SOCS-6 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for SOCS-6 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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