SOD1/Cu-Zn SOD Antibody (6F1) - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-59422

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Human

Applications

ELISA, Flow Cytometry, Immunocytochemistry/ Immunofluorescence, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 kappa Clone # 6F1

Format

BSA Free

Concentration

1 mg/ml

View all SOD1/Cu-Zn SOD Antibodies »

Product Specifications

Immunogen

Recombinant human SOD1/Cu-Zn SOD (1-154aa) purified from E. coli

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1 kappa

Scientific Data Images for SOD1/Cu-Zn SOD Antibody (6F1) - BSA Free

Western Blot: SOD1/Cu-Zn SOD Antibody (6F1)BSA Free [NBP2-59422]

Western Blot: SOD1/Cu-Zn SOD Antibody (6F1)BSA Free [NBP2-59422]

Western Blot: SOD1/Cu-Zn SOD Antibody (6F1) [NBP2-59422] - Lane 1: Recombinant protein SOD1, Lane 2: Recombinant protein SOD2
Immunocytochemistry/ Immunofluorescence: SOD1/Cu-Zn SOD Antibody (6F1) - BSA Free [NBP2-59422]

Immunocytochemistry/ Immunofluorescence: SOD1/Cu-Zn SOD Antibody (6F1) - BSA Free [NBP2-59422]

Immunocytochemistry/Immunofluorescence: SOD1/Cu-Zn SOD Antibody (6F1) [NBP2-59422] - Analysis of SOD1 in Hep3B cells line, stained with DAPI (Blue) for nucleus staining and monoclonal anti-human SOD1 antibody (1:100) with goat anti-mouse IgG-Alexa fluor 488 conjugate (Green).

Applications for SOD1/Cu-Zn SOD Antibody (6F1) - BSA Free

Application
Recommended Usage

Flow Cytometry

1:10-1:1032

Immunocytochemistry/ Immunofluorescence

1:100

Western Blot

1:1000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS (pH 7.4), 10% Glycerol

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: SOD1/Cu-Zn SOD

FUNCTION: Destroys radicals which are normally produced within the cells and which are toxic to biological systems. CATALYTIC ACTIVITY: 2 superoxide + 2 H+ = O2 + H2O2. COFACTOR: Binds 1 copper ion per subunit. COFACTOR: Binds 1 zinc ion per subunit. SUBUNIT: Homodimer. SUBCELLULAR LOCATION: Cytoplasm. DISEASE: Defects in SOD1 are the cause of familial amyotrophic lateral sclerosis (FALS); also called amyotrophic lateral sclerosis 1 (ALS1 or ALS). ALS is a degenerative disorder of motorneurons in the cortex, brainstem and spinal cord. ALS is characterized by muscular weakness and atrophy beginning in the hands and spreading to the forearms and legs. Muscle fasciculations are commonly visible. Sensory abnormalities are absent. Death usually occurs within 2 to 5 years. ALS is sometimes referred to as Lou Gehrig disease after the famous American baseball player who was diagnosed with the disorder. FALS, the familial form of ALS, accounts for about 10% of the cases and is transmitted in an autosomal dominant manner. The mean age at onset of FALS is 45 years. MISCELLANEOUS: Zinc binding promotes dimerization. SIMILARITY: Belongs to the Cu-Zn superoxide dismutase family.

Long Name

Superoxide Dismutase-1

Alternate Names

Cu-Zn SOD, CuZn SOD, Ipo1, IPOA, SOD, cytosolic, SOD, Soluble

Gene Symbol

SOD1

Additional SOD1/Cu-Zn SOD Products

Product Documents for SOD1/Cu-Zn SOD Antibody (6F1) - BSA Free

Product Datasheets

Certificate of Analysis

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Product Specific Notices for SOD1/Cu-Zn SOD Antibody (6F1) - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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