Somatostatin R3/SSTR3 Antibody (7H8E5) - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-37266

Novus Biologicals, part of Bio-Techne
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NBP2-37266
NBP2-37266-0.025ml
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Key Product Details

Species Reactivity

Validated:

Human, Rat

Applications

CyTOF-ready, ELISA, Flow Cytometry, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # 7H8E5

Format

BSA Free

Concentration

1 mg/ml

View all Somatostatin R3/SSTR3 Antibodies »

Product Summary for Somatostatin R3/SSTR3 Antibody (7H8E5) - BSA Free

Immunogen

Purified recombinant fragment of human Somatostatin R3/SSTR3 (AA: 1-43) expressed in E. Coli.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Theoretical MW

45.8 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for Somatostatin R3/SSTR3 Antibody (7H8E5) - BSA Free

Western Blot: Somatostatin R3/SSTR3 Antibody (7H8E5)BSA Free [NBP2-37266]

Western Blot: Somatostatin R3/SSTR3 Antibody (7H8E5)BSA Free [NBP2-37266]

Western Blot: Somatostatin R3/SSTR3 Antibody (7H8E5) [NBP2-37266] - Western blot analysis using SSTR3 mouse mAb against Hela (1), PANC-1 (2), PC-12 (3),SK-N-SH (4), U937 (5) and HepG2 (6) cell lysate.
Flow Cytometry: Somatostatin R3/SSTR3 Antibody (7H8E5) - BSA Free [NBP2-37266]

Flow Cytometry: Somatostatin R3/SSTR3 Antibody (7H8E5) - BSA Free [NBP2-37266]

Flow Cytometry: Somatostatin R3/SSTR3 Antibody (7H8E5) [NBP2-37266] - Flow cytometric analysis of Hela cells using SSTR3 mouse mAb (green) and negative control (red).
Western Blot: Somatostatin R3/SSTR3 Antibody (7H8E5)BSA Free [NBP2-37266]

Western Blot: Somatostatin R3/SSTR3 Antibody (7H8E5)BSA Free [NBP2-37266]

Western Blot: Somatostatin R3/SSTR3 Antibody (7H8E5) [NBP2-37266] - Western blot analysis using SSTR3 mAb against human SSTR3 (AA: 1-43) recombinant protein. (Expected MW is 30.2 kDa)
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Applications for Somatostatin R3/SSTR3 Antibody (7H8E5) - BSA Free

Application
Recommended Usage

ELISA

1:10000

Flow Cytometry

1:200 - 1:400

Western Blot

1:500 - 1:2000
Application Notes
This antibody is Cytof ready.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein G purified

Formulation

PBS

Format

BSA Free

Preservative

0.05% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Somatostatin R3/SSTR3

Expression of Somatostatin Receptor Type 3 (SSTR3) has been reported in brain, breast, eye, gastrointestinal tract, pancreas, and thyroid. G-protein Coupled Receptors (GPCRs) comprise one of the largest families of signaling molecules with more than a thousand members currently predicted to exist. All GPCRs share a structural motif consisting of seven membrane-spanning helices, and exist in both active and inactive forms. An array of activating ligands participate in the conformation of GPCRs which leads to signaling via G-proteins and downstream effectors. Ongoing studies have also shown the vast series of reactions which participate in the negative regulation of GPCRs. This "turn-off" activity has tremendous implications for the physiological action of the cell, and continues to drive pharmacological research for new drug candidates. Two blockbuster drugs which have been developed as GPCR-targeted pharmaceuticals are Zyprexa (Eli Lilly) and Claritin (Schering-Plough) which have multi-billion dollar shares of the mental health and allergy markets, respectively.

Long Name

Somatostatin Receptor Type 3

Alternate Names

SomatostatinR3, SSR-28, SST3, SSTR3

Gene Symbol

SSTR3

Additional Somatostatin R3/SSTR3 Products

Product Documents for Somatostatin R3/SSTR3 Antibody (7H8E5) - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Somatostatin R3/SSTR3 Antibody (7H8E5) - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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