SorLA Antibody (3B6B11) - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-28882

Novus Biologicals, part of Bio-Techne
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NBP1-28882
NBP1-28882-0.025ml
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Key Product Details

Species Reactivity

Human

Applications

ELISA, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # 3B6B11

Format

BSA Free

Concentration

This product is unpurified. The exact concentration of antibody is not quantifiable.

View all SorLA Antibodies »

Product Specifications

Immunogen

Purified recombinant fragment of human SorLA expressed in E. Coli.

Specificity

Specific for SORL1.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Scientific Data Images for SorLA Antibody (3B6B11) - BSA Free

Western Blot: SorLA Antibody (3B6B11)BSA Free [NBP1-28882]

Western Blot: SorLA Antibody (3B6B11)BSA Free [NBP1-28882]

Western Blot: SorLA Antibody (3B6B11) [NBP1-28882] - Analysis using SORL1 mouse mAb against truncated SORL1 recombinant protein.
Immunocytochemistry/ Immunofluorescence: SorLA Antibody (3B6B11) - BSA Free [NBP1-28882]

Immunocytochemistry/ Immunofluorescence: SorLA Antibody (3B6B11) - BSA Free [NBP1-28882]

Immunocytochemistry/Immunofluorescence: SorLA Antibody (3B6B11) [NBP1-28882] - Analysis of PANC-1 cells using SORL1 mouse mAb (green). Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin. Blue: DRAQ5 fluorescent DNA dye.
Immunohistochemistry-Paraffin: SorLA Antibody (3B6B11) - BSA Free [NBP1-28882]

Immunohistochemistry-Paraffin: SorLA Antibody (3B6B11) - BSA Free [NBP1-28882]

Immunohistochemistry-Paraffin: SorLA Antibody (3B6B11) [NBP1-28882] - Analysis of human cerebrum tissues using SORL1 mouse mAb with DAB staining.
View 1 more images

Applications for SorLA Antibody (3B6B11) - BSA Free

Application
Recommended Usage

ELISA

1:10000

Immunocytochemistry/ Immunofluorescence

1:200 - 1:1000

Immunohistochemistry

1:200 - 1:1000

Immunohistochemistry-Paraffin

1:200 - 1:1000

Western Blot

1:500 - 1:2000

Formulation, Preparation, and Storage

Purification

Unpurified

Formulation

Ascites

Format

BSA Free

Preservative

0.03% Sodium Azide

Concentration

This product is unpurified. The exact concentration of antibody is not quantifiable.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: SorLA

SORL1 (sortilin-related receptor, L A repeats containing) also known as sorting protein-related receptor containing LDLR class A (SorLA), is a Type I membrane protein that may be involved in cell-cell interaction. SorLA, a single transmembrane receptor, binds LDL and transports it into cells by endocytosis. SorLA is synthesized as a proreceptor which is processed to the mature form by a furin-like propeptidase. It can also bind to RAP (receptor-associated protein). SorLA is a multifunctional endocytis receptor important in lipoprotein and protease uptake. The N-terminal propeptide, which is removed, can be cleaved by furin or homologous proteases. Endogenous SorLA binds the neuropeptide head activator (HA) and is important for HA signaling and function. The gene encoding for the protein maps to chromosome 8p23.1. SorLA is expressed mainly in brain (cerebral cortex, cerebellum and the occipital pole), but can also be found in liver, spinal cord, kidney, testis and pancreas.

Long Name

Sortilin-related Receptor Containing LDLR Class A Repeats

Alternate Names

gp250, LR11, LRP9, SORL1

Entrez Gene IDs

6653 (Human)

Gene Symbol

SORL1

UniProt

Q92673

Additional SorLA Products

Product Documents for SorLA Antibody (3B6B11) - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for SorLA Antibody (3B6B11) - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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