Key Product Details

Validated by

Independent Antibodies

Species Reactivity

Validated:

Human

Predicted:

Mouse (100%). Backed by our 100% Guarantee.

Applications

Immunoprecipitation, Western Blot (Negative)

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

1.0 mg/ml

View all SOS1 Antibodies »

Product Specifications

Immunogen

The immunogen recognized by this antibody maps to a region between residue 1025 and 1075 of human son of sevenless ortholog 1 using the numbering given in entry NP_005624.2 (GeneID 6654).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for SOS1 Antibody

Immunoprecipitation: SOS1 Antibody [NBP1-05954]

Immunoprecipitation: SOS1 Antibody [NBP1-05954]

Immunoprecipitation: SOS1 Antibody [NBP1-05954] - Whole cell lysate (1 mg for IP, 20% of IP loaded) from HeLa cells. Affinity purified rabbit anti-SOS1 antibody used for IP at 3 mcg/mg lysate. SOS1 was also immunoprecipitated by rabbit anti-SOS1 antibody NBP1-05955, which recognizes a downstream epitope.

Applications for SOS1 Antibody

Application
Recommended Usage

Immunoprecipitation

2-5 ug/mg lysate
Application Notes
Western Blot Not recommended. Use rabbit anti-SOS1 antibody NBP1-05955.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris-Citrate/Phosphate (pH 7.0 - 8.0)

Preservative

0.09% Sodium Azide

Concentration

1.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: SOS1

This gene encodes a protein that is a guanine nucleotide exchange factor for RAS proteins, membrane proteins that bind guanine nucleotides and participate in signal transduction pathways. GTP binding activates and GTP hydrolysis inactivates RAS proteins. The product of this gene may regulate RAS proteins by facilitating the exchange of GTP for GDP. Mutations in this gene are associated with gingival fibromatosis 1 and Noonan syndrome type 4. [provided by RefSeq]

Long Name

Son of sevenless homolog 1

Alternate Names

SOS-1

Entrez Gene IDs

6654 (Human)

Gene Symbol

SOS1

UniProt

NP_005624.2 (Human)

Additional SOS1 Products

Product Documents for SOS1 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for SOS1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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