SP-D Antibody (001)

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-90939

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP2-90939-50ul
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Key Product Details

Species Reactivity

Validated:

Rhesus Macaque

Applications

Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # 001

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all SP-D Antibodies »

Product Summary for SP-D Antibody (001)

Immunogen

This antibody was obtained from a rabbit immunized with purified, recombinant Rhesus SP-D (Accession#: NP_001035283.1; Met1-Phe375).

Specificity

No cross-reactivity in ELISA with: Human SFTPD

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Description

This antibody can be stored at 2C-8C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20C to -80C. Avoid repeated freeze-thaw cycles.

Scientific Data Images for SP-D Antibody (001)

Immunohistochemistry-Paraffin: SP-D Antibody (001) [NBP2-90939]

Immunohistochemistry-Paraffin: SP-D Antibody (001) [NBP2-90939]

Immunohistochemistry-Paraffin: SP-D Antibody (001) [NBP2-90939] - Immunochemical staining of Rhesus SP-D in Rhesus lung with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections).

Applications for SP-D Antibody (001)

Application
Recommended Usage

Immunohistochemistry-Paraffin

1:100-1:500
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

0.2 um filtered solution in PBS

Preservative

No Preservative

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: SP-D

Surfactant protein D (SP-D) is synthesized and secreted by lung epithelial cells. It belongs to group III of the family of C-type lectins and members of this group has overall structure consisting of multiple globular head regions linked by triple-helical, collagen-like, strands. This group also includes SP-A and the serum proteins mannan-binding protein, conglutinin and collectin-43, all of which have been shown to bind to the C1q receptor found on a wide variety of cells. Both SP-D and SP-A have been shown to enhance oxygen radical production by alveolar macrophages. The serum concentration is 88 ng/ml in healthy individuals (2).

Long Name

Surfactant Pulmonary Associated Protein D

Alternate Names

Collectin 7, PSP-D, SFTP4, SFTPD, SPD

Gene Symbol

SFTPD

Additional SP-D Products

Product Documents for SP-D Antibody (001)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for SP-D Antibody (001)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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