SPAG8 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-54628

Novus Biologicals, part of Bio-Techne
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NBP1-54628
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Key Product Details

Species Reactivity

Human

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

0.5 mg/ml

View all SPAG8 Antibodies »

Product Specifications

Immunogen

Synthetic peptides corresponding to SPAG8(sperm associated antigen 8) The peptide sequence was selected from the middle region of SPAG8. Peptide sequence PAPTKPHDYRQEQPETFWIQRAPQLPTWWPLPTQVPAAEDYLTWKEWGFT. The peptide sequence for this immunogen was taken from within the described region.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

53 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Description

The addition of 50% glycerol is optional for those storing this antibody at -20C and not aliquoting smaller units. However, please note that glycerol may interrupt some downstream antibody applications and should be added with caution.

Scientific Data Images for SPAG8 Antibody

Western Blot: SPAG8 Antibody [NBP1-54628]

Western Blot: SPAG8 Antibody [NBP1-54628]

Western Blot: SPAG8 Antibody [NBP1-54628] - Hela cell lysate, concentration 0.2-1 ug/ml.

Applications for SPAG8 Antibody

Application
Recommended Usage

Western Blot

1.0 ug/ml

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, 2% Sucrose

Preservative

0.09% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: SPAG8

The correlation of anti-sperm antibodies with cases of unexplained infertility implicates a role for these antibodies in blocking fertilization. Improved diagnosis and treatment of immunologic infertility, as well as identification of proteins for targeted contraception, are dependent on the identification and characterization of relevant sperm antigens. SPAG8 is recognized by sperm agglutinating antibodies from an infertile woman. This protein is localized in germ cells of the testis at all stages of spermatogenesis and is localized to the acrosomal region of mature spermatozoa.The correlation of anti-sperm antibodies with cases of unexplained infertility implicates a role for these antibodies in blocking fertilization. Improved diagnosis and treatment of immunologic infertility, as well as identification of proteins for targeted contraception, are dependent on the identification and characterization of relevant sperm antigens. The protein encoded by this gene is recognized by sperm agglutinating antibodies from an infertile woman. This protein is localized in germ cells of the testis at all stages of spermatogenesis and is localized to the acrosomal region of mature spermatozoa. Alternatively spliced variants that encode different protein isoforms have been described but the full-length sequences of only two have been determined.

Alternate Names

BS-84, HSD-1MGC26201, hSMP-1, SMP1, SMP-1, SPAG3, sperm associated antigen 8, Sperm membrane protein 1, Sperm membrane protein BS-84, sperm-associated antigen 8

Gene Symbol

SPAG8

UniProt

Q99932-2 (Human)

Additional SPAG8 Products

Product Documents for SPAG8 Antibody

Product Datasheets

Certificate of Analysis

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Product Specific Notices for SPAG8 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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