SPAG8 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-20464

Novus Biologicals, part of Bio-Techne
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NBP2-20464
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Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all SPAG8 Antibodies »

Product Specifications

Immunogen

Recombinant protein encompassing a sequence within the center region of human SPAG8. The exact sequence is proprietary.

Localization

Acrosome

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

45 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for SPAG8 Antibody

Western Blot: SPAG8 Antibody [NBP2-20464]

Western Blot: SPAG8 Antibody [NBP2-20464]

Western Blot: SPAG8 Antibody [NBP2-20464] - Sample (30 ug of whole cell lysate) A: U87-MG 10% SDS PAGE gel, diluted at 1:1000.
Immunohistochemistry-Paraffin: SPAG8 Antibody [NBP2-20464]

Immunohistochemistry-Paraffin: SPAG8 Antibody [NBP2-20464]

Immunohistochemistry-Paraffin: SPAG8 Antibody [NBP2-20464] - Immunohistochemical analysis of paraffin-embedded Colon ca, using antibody at 1:500 dilution.

Applications for SPAG8 Antibody

Application
Recommended Usage

Immunohistochemistry

1:100-1:1000

Immunohistochemistry-Paraffin

1:100-1:1000

Western Blot

1:500-1:3000

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

PBS (pH 7), 20% Glycerol, 1% BSA

Preservative

0.01% Thimerosal

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: SPAG8

The correlation of anti-sperm antibodies with cases of unexplained infertility implicates a role for these antibodies in blocking fertilization. Improved diagnosis and treatment of immunologic infertility, as well as identification of proteins for targeted contraception, are dependent on the identification and characterization of relevant sperm antigens. The protein encoded by this gene is recognized by sperm agglutinating antibodies from an infertile woman. This protein is localized in germ cells of the testis at all stages of spermatogenesis and is localized to the acrosomal region of mature spermatozoa. Alternatively spliced variants that encode different protein isoforms have been described but the full-length sequences of only two have been determined. [provided by RefSeq]

Alternate Names

BS-84, HSD-1MGC26201, hSMP-1, SMP1, SMP-1, SPAG3, sperm associated antigen 8, Sperm membrane protein 1, Sperm membrane protein BS-84, sperm-associated antigen 8

Gene Symbol

SPAG8

Additional SPAG8 Products

Product Documents for SPAG8 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for SPAG8 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

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