Speedy/Ringo Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-49476

Novus Biologicals, part of Bio-Techne
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NBP2-49476
NBP2-49476-25ul
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Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Validated:

Human

Predicted:

Mouse (97%), Rat (94%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Speedy/Ringo Antibodies »

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to amino acids: CCEEVMAIAPTHYIWQRERSVHHSGAVRNYNRDEVQLPRGPSATPVDCSLCGKKRRYVRLGLSSSSS

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Speedy/Ringo Antibody

Immunohistochemistry-Paraffin: Speedy/Ringo Antibody [NBP2-49476]

Immunohistochemistry-Paraffin: Speedy/Ringo Antibody [NBP2-49476]

Immunohistochemistry-Paraffin: Speedy/Ringo Antibody [NBP2-49476] - Staining in human testis and fallopian tube tissues using anti-SPDYA antibody. Corresponding SPDYA RNA-seq data are presented for the same tissues.
Immunohistochemistry-Paraffin: Speedy/Ringo Antibody [NBP2-49476]

Immunohistochemistry-Paraffin: Speedy/Ringo Antibody [NBP2-49476]

Immunohistochemistry-Paraffin: Speedy/Ringo Antibody [NBP2-49476] - Staining of human testis shows high expression.
Immunohistochemistry-Paraffin: Speedy/Ringo Antibody [NBP2-49476]

Immunohistochemistry-Paraffin: Speedy/Ringo Antibody [NBP2-49476]

Immunohistochemistry-Paraffin: Speedy/Ringo Antibody [NBP2-49476] - Staining of human fallopian tube shows low expression as expected.

Applications for Speedy/Ringo Antibody

Application
Recommended Usage

Immunohistochemistry

1:200 - 1:500

Immunohistochemistry-Paraffin

1:200 - 1:500
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Speedy/Ringo

Speedy/Ringo (Spy1 or SPDYA) regulates the G1/S phase transition of the cell cycle by binding and activating CDC2, CDK2 and CDKN1B/KIP1. It mediates cell survival during the DNA damage process through activation of CDK2. Tight regulation of Speedy is important for the somatic cell cycle. Speedy overexpression has been linked to hepatocellular cancer.

Alternate Names

hSpy/Ringo A, MGC110856, Rapid inducer of G2/M progression in oocytes A, RINGO A, RINGO3, SPDY1, speedy homolog 1 (Drosophila), speedy homolog A (Xenopus laevis), speedy protein A, speedy-1, Spy1, SPY1MGC57218

Gene Symbol

SPDYA

Additional Speedy/Ringo Products

Product Documents for Speedy/Ringo Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Speedy/Ringo Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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