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Sphingosine Kinase 2/SPHK2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-23423

Novus Biologicals, part of Bio-Techne
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NBP3-23423

Key Product Details

Validated by

Biological Validation

Species Reactivity

Validated:

Human, Mouse, Rat

Applications

Immunocytochemistry/ Immunofluorescence, Immunoprecipitation, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Product Summary for Sphingosine Kinase 2/SPHK2 Antibody

Immunogen

Sphingosine Kinase 2/SPHK2 (N-terminal region) synthetic peptide (coupled to KLH) corresponding to amino acid residues in the N-terminal region of human Sphingosine Kinase 2/SPHK2. This peptide sequence is highly conserved in rat and mouse Sphingosine Kinase 2/SPHK2 proteins, and has no homology to SK1. [UniProt# Q9NRA0]

Specificity

The antibody detects 70 kDa proteins corresponding to the molecular mass of Sphingosine Kinase 2/SPHK2 on SDS-PAGE immunoblots of human recombinant Sphingosine Kinase 2/SPHK2 and endogenous Sphingosine Kinase 2/SPHK2 in human HeLa cells.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

70 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Description

Stable for at least 1 year at -20°C.

Scientific Data Images for Sphingosine Kinase 2/SPHK2 Antibody

Sphingosine Kinase 2/SPHK2 Antibody

Western Blot: Sphingosine Kinase 2/SPHK2 Antibody [NBP3-23423] -

Western Blot: Sphingosine Kinase 2/SPHK2 Antibody [NBP3-23423] - Western blot of human recombinant Sphingosine Kinase 2/SPHK2 (lanes 1-4) and HeLa treated with calyculin A (lanes 5-8). The blots were untreated (lane 1, 3, 5 & 7) or treated with lambda phosphatase (lane 2, 4, 6 & 8), then probed with anti-Sphingosine Kinase 2/SPHK2 (N-terminal region) (lanes 1, 2, 5 & 6) or anti-Sphingosine Kinase 2/SPHK2 (Thr-578) (lanes 3, 4, 7, & 8).

Applications for Sphingosine Kinase 2/SPHK2 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:100

Immunoprecipitation

1:100

Western Blot

1:250
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

PBS, 1 mg/ml BSA and 50% glycerol

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C.

Background: Sphingosine Kinase 2/SPHK2

SPHK2 catalyzes the reduction of free and protein-bound methionine sulfoxide to methionine

Alternate Names

SK2, SPK2

Gene Symbol

SPHK2

Additional Sphingosine Kinase 2/SPHK2 Products

Product Documents for Sphingosine Kinase 2/SPHK2 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Sphingosine Kinase 2/SPHK2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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