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SPR Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-33546

Novus Biologicals, part of Bio-Techne
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NBP1-33546

Key Product Details

Species Reactivity

Validated:

Human, Mouse

Predicted:

Rhesus Macaque (97%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunoprecipitation, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

Recombinant protein encompassing a sequence within the center region of human SPR. The exact sequence is proprietary.

Reactivity Notes

Bovine (82%), Rabbit (86%).

Localization

Cytoplasm

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

28 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for SPR Antibody

Western Blot: SPR Antibody [NBP1-33546]

Western Blot: SPR Antibody [NBP1-33546]

Western Blot: SPR Antibody [NBP1-33546] - Sample (30 ug of whole cell lysate) A: A431 12% SDS PAGE; antibody diluted at 1:1000.
Immunocytochemistry/ Immunofluorescence: SPR Antibody [NBP1-33546]

Immunocytochemistry/ Immunofluorescence: SPR Antibody [NBP1-33546]

Immunocytochemistry/Immunofluorescence: SPR Antibody [NBP1-33546] - Analysis of methanol-fixed HeLa, using antibody at 1:200 dilution.
Immunohistochemistry-Paraffin: SPR Antibody [NBP1-33546]

Immunohistochemistry-Paraffin: SPR Antibody [NBP1-33546]

Immunohistochemistry-Paraffin: SPR Antibody [NBP1-33546] - Paraffin-embedded mouse fore brain. SPR antibody [N2C3] dilution: 1:500.

Applications for SPR Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:100-1:1000

Immunohistochemistry

1:100-1:1000

Immunohistochemistry-Paraffin

1:100-1:1000

Immunoprecipitation

1:100-1:500

Western Blot

1:500-1:3000

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

0.1M Tris (pH 7), 0.1M Glycine, 20% Glycerol

Preservative

0.01% Thimerosal

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: SPR

This gene encodes an aldo-keto reductase that catalyzes the NADPH-dependent reduction of pteridine derivatives and is important in the biosynthesis of tetrahydrobiopterin (BH4). Mutations in this gene result in DOPA-responsive dystonia due to sepiaterin reductase deficiency. A pseudogene has been identified on chromosome 1.

Long Name

Sepiapterin Reductase

Alternate Names

EC 1.1.1.153, Gm10328, SDR38C1

Gene Symbol

SPR

Additional SPR Products

Product Documents for SPR Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for SPR Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.