SR-AI/MSR Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-88125

Novus Biologicals, part of Bio-Techne
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NBP1-88125
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Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all SR-AI/MSR Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: KWETKNCSVSSTNANDITQSLTGKGNDSEEEMRFQEVFMEHMSNMEKRIQHILDMEANLMDTEHFQNFSMTTDQRFNDILLQLSTLFSSVQGHGNAIDEISKSLISLNTTLLDLQLNIENL

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for SR-AI/MSR Antibody

Immunohistochemistry-Paraffin: SR-AI/MSR Antibody [NBP1-88125]

Immunohistochemistry-Paraffin: SR-AI/MSR Antibody [NBP1-88125]

Immunohistochemistry-Paraffin: SR-AI/MSR Antibody [NBP1-88125] - Staining in human lung and cerebral cortex tissues.. Corresponding MSR1 RNA-seq data are presented for the same tissues.
Western Blot: SR-AI/MSR Antibody [NBP1-88125]

Western Blot: SR-AI/MSR Antibody [NBP1-88125]

Western Blot: SR-AI/MSR Antibody [NBP1-88125] - Analysis in control (vector only transfected HEK293T lysate) and mSR1 over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (3.1 kDa) in mammalian HEK293T cells).
Immunohistochemistry-Paraffin: SR-AI/MSR Antibody [NBP1-88125]

Immunohistochemistry-Paraffin: SR-AI/MSR Antibody [NBP1-88125]

Immunohistochemistry-Paraffin: SR-AI/MSR Antibody [NBP1-88125] - Staining of human liver shows strong cytoplasmic positivity in Kupffer cells.
View 4 more images

Applications for SR-AI/MSR Antibody

Application
Recommended Usage

Immunohistochemistry

1:1000 - 1:2500

Immunohistochemistry-Paraffin

1:1000 - 1:2500

Western Blot

0.04-0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: SR-AI/MSR

Macrophage scavenger receptors (MSR) are membrane glycoproteins that mediate the recognition and uptake of a variety of macromolecules, including modified lipoproteins, advanced glycation end (AGEs) products and amyloid b-protein (Abeta). While the normal role of MSR is associated with cell adhesion and host defense mechanisms, it also has been implicated in the development of atherosclerosis and Abeta deposition in Alzheimer's disease (AD).

In cell cultures, macrophage scavenger receptor has been shown to mediate adhesion of macrophages and other cell lines to tissue culture plastic. MSR1 antibodies are useful for research on atherosclerosis, Alzheimer's disease, and host defense.

Long Name

Macrophage Scavenger Receptor Types I and II

Alternate Names

CD204, MSR1, SCARA1, SRAI

Entrez Gene IDs

4481 (Human)

Gene Symbol

MSR1

UniProt

P21757

Additional SR-AI/MSR Products

Product Documents for SR-AI/MSR Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for SR-AI/MSR Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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