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SRCAP Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-76468

Novus Biologicals, part of Bio-Techne
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NBP2-76468

Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat, Canine

Applications

Immunocytochemistry/ Immunofluorescence, Peptide ELISA

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG

Concentration

0.5 mg/ml

Product Summary for SRCAP Antibody

Immunogen

Peptide with sequence C-DEAQNIKNFKSQR corresponding to internal region according to NP_006653.2.

Epitope

internal region

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Scientific Data Images for SRCAP Antibody

Immunofluorescence: SRCAP Antibody [NBP2-76468]

Immunofluorescence: SRCAP Antibody [NBP2-76468]

Immunofluorescence: SRCAP Antibody [NBP2-76468] - Analysis of paraformaldehyde fixed A431 cells, permeabilized with 0.15% Triton. Primary incubation 1hr (10ug/ml) followed by Alexa Fluor 488 secondary antibody (2ug/ml), showing nuclear staining. The nuclear stain is DAPI (blue). Negative control: Unimmunized goat IgG (10ug/ml) followed by Alexa Fluor 488 secondary antibody (2ug/ml).

Applications for SRCAP Antibody

Application
Recommended Usage

Peptide ELISA

Detection limit 1:8000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA

Preservative

0.02% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: SRCAP

Catalytic component of the SRCAP complex which mediates the ATP-dependent exchange of histone H2AZ/H2B dimers for nucleosomal H2A/H2B, leading to transcriptional regulation of selected genes by chromatin remodeling. Acts as a coactivator for CREB-mediated transcription, steroid receptor-mediated transcription, and Notch-mediated transcription

Alternate Names

domino homolog 1, Domino homolog 2, DOMO1, EAF1, EC 3.6.1, EC 3.6.4.-, FLJ44499, KIAA0309helicase SRCAP, Snf2-related CBP activator, Snf2-related CREBBP activator protein, Swi2/Snf2-related ATPase homolog, domino homolog 1, SWR1Snf2-related CBP activator protein

Gene Symbol

SRCAP

Additional SRCAP Products

Product Documents for SRCAP Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for SRCAP Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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