SRGAP2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-88830

Novus Biologicals, part of Bio-Techne
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NBP1-88830
NBP1-88830-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (98%), Rat (98%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all SRGAP2 Antibodies »

Product Summary for SRGAP2 Antibody

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: WEGRHNGIDGLIPHQYIVVQDTEDGVVERSSPKSEIEVISEPPEEKVTARAGASCPSGGHVADIYLANINKQRKRPESGSIR

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for SRGAP2 Antibody

Western Blot: SRGAP2 Antibody [NBP1-88830]

Western Blot: SRGAP2 Antibody [NBP1-88830]

Western Blot: SRGAP2 Antibody [NBP1-88830] - Lane 1: Marker [kDa] 250, 130, 100, 70, 55, 35, 25, 15, 10
Lane 2: Human cell line SK-MEL-30
Immunocytochemistry/ Immunofluorescence: SRGAP2 Antibody [NBP1-88830]

Immunocytochemistry/ Immunofluorescence: SRGAP2 Antibody [NBP1-88830]

Immunocytochemistry/Immunofluorescence: SRGAP2 Antibody [NBP1-88830] - Staining of human cell line A-431 shows localization to nucleoplasm & cytosol. Antibody staining is shown in green.
Immunohistochemistry-Paraffin: SRGAP2 Antibody [NBP1-88830]

Immunohistochemistry-Paraffin: SRGAP2 Antibody [NBP1-88830]

Immunohistochemistry-Paraffin: SRGAP2 Antibody [NBP1-88830] - Staining of human cerebral cortex shows moderate to strong cytoplasmic positivity in neurons.
View 3 more images

Applications for SRGAP2 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200

Western Blot

0.04-0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval method is recommended. ICC/IF, Fixation Permeabilization: Use PFA/Triton X-100.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: SRGAP2

SRGAP2, also known as SLIT-ROBO Rho GTPase-activating protein 2, is a 121 kDa 1071 amino acid protein. Throughout the development of the cerebral cortex SRGAP2 has a significant role in neuronal morphogenesis. Current research on SRGAP2 is being conducted in relation to neuronitis, pilocytic astrocytoma, infantile epileptic encephalopathy and schizophrenia. SRGAP2 is linked to the long-term memory, axon guidance, localization, brain development and cell migration pathways where it interacts with FASLG, YWHAG, YWHAZ, DISC1 and MYO1G.

Alternate Names

FNBP2, Formin-binding protein 2, KIAA0456ARHGAP34formin binding protein 2, Rho GTPase-activating protein 34, SLIT-ROBO Rho GTPase activating protein 2, SLIT-ROBO Rho GTPase-activating protein 2, srGAP2, SRGAP3

Entrez Gene IDs

23380 (Human)

Gene Symbol

SRGAP2

UniProt

O75044 (Human)

Additional SRGAP2 Products

Product Documents for SRGAP2 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for SRGAP2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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