SRGN Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-80886

Novus Biologicals, part of Bio-Techne
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NBP1-80886
NBP1-80886-25ul
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Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Validated:

Human

Cited:

Human

Applications

Validated:

Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunoprecipitation, Western Blot

Cited:

Flow Cytometry, Immunoprecipitation, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Serglycin/SRGN Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: MQKLLKCSRLVLALALILVLESSVQGYPTRRARYQWVRCNPDSNSANCLEEKGPMFELLPGESNKIPRLRTDLFPKTRIQDLNRIFPLSEDYSGSGFGSGSGSGSGSGSGFLTEMEQDYQLVDE

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for SRGN Antibody

Immunohistochemistry-Paraffin: SRGN Antibody [NBP1-80886]

Immunohistochemistry-Paraffin: SRGN Antibody [NBP1-80886]

Immunohistochemistry-Paraffin: SRGN Antibody [NBP1-80886] - Analysis in human bone marrow and skeletal muscle tissues using NBP1-80886 antibody. Corresponding SRGN RNA-seq data are presented for the same tissues.
Western Blot: SRGN Antibody [NBP1-80886]

Western Blot: SRGN Antibody [NBP1-80886]

Western Blot: SRGN Antibody [NBP1-80886] - Analysis in human cell lines A-549 and Caco-2. Corresponding RNA-seq data are presented for the same cell lines. Loading control: Anti-GAPDH.
Immunohistochemistry-Paraffin: SRGN Antibody [NBP1-80886]

Immunohistochemistry-Paraffin: SRGN Antibody [NBP1-80886]

Immunohistochemistry-Paraffin: SRGN Antibody [NBP1-80886] - Staining of human skeletal muscle shows no positivity in myocytes as expected.
View 3 more images

Applications for SRGN Antibody

Application
Recommended Usage

Flow Cytometry

Reported in scientific literature (PMID: 24403068)

Immunohistochemistry

1:1000 - 1:2500

Immunohistochemistry-Paraffin

1:1000 - 1:2500

Immunoprecipitation

Reported in scientific literature (PMID: 26694746)

Western Blot

0.04 - 0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Serglycin/SRGN

SRGN encodes a protein best known as a hematopoietic cell granule proteoglycan. Proteoglycans stored in the secretory granules of many hematopoietic cells also contain a protease-resistant peptide core, which may be important for neutralizing hydrolytic enzymes. This encoded protein was found to be associated with the macromolecular complex of granzymes and perforin, which may serve as a mediator of granule-mediated apoptosis. [provided by RefSeq]

Long Name

Hematopoietic Proteoglycan Core Protein

Alternate Names

SRGN

Entrez Gene IDs

5552 (Human)

Gene Symbol

SRGN

UniProt

P10124 (Human)

Additional Serglycin/SRGN Products

Product Documents for SRGN Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for SRGN Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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