Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Predicted:

Bovine (100%). Backed by our 100% Guarantee.

Applications

ELISA, Immunocytochemistry/ Immunofluorescence, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1 mg/ml

View all ST3GAL6 Antibodies »

Product Specifications

Immunogen

Antibody was raised against a 16 amino acid synthetic peptide from near the carboxy terminus of human ST3gal6. The immunogen is located within amino acids 230 - 280 of ST3gal6. Amino Acid Squence: PKVFPKNQKPKHPTTG

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for ST3GAL6 Antibody - BSA Free

Western Blot: ST3GAL6 AntibodyBSA Free [NBP1-77353]

Western Blot: ST3GAL6 AntibodyBSA Free [NBP1-77353]

Western Blot: ST3GAL6 Antibody [NBP1-77353] - HeLa cell lysate with ST3gal6 antibody at (A) 1 and (B) 2 ug/mL.
ST3GAL6 Antibody - BSA Free

Immunocytochemistry/ Immunofluorescence: ST3GAL6 Antibody - BSA Free [NBP1-77353] -

Immunocytochemistry/ Immunofluorescence: ST3GAL6 Antibody - BSA Free [NBP1-77353] - Immunocytochemistry of ST3GAL6 in HeLa cells with ST3GAL6 antibody at 5 ug/mL.

Applications for ST3GAL6 Antibody - BSA Free

Application
Recommended Usage

ELISA

1:100-1:2000

Immunocytochemistry/ Immunofluorescence

5 ug/ml

Western Blot

1-2 ug/ml

Formulation, Preparation, and Storage

Purification

Peptide affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: ST3GAL6

Sialyltransferases catalyze the transfer of sialic acid from cytidine 5-prime monophospho-N-acetylneuraminic acid (CMP-NeuAc) to terminal positions of glycoprotein and glycolipid carbohydrate groups. Terminal NeuAc residues are key determinants of carbohydrate structures, such as the sialyl-Lewis X determinants, and are widely distributed in many cell types. However, cancer cells often express more heavily sialylated glycans on their cell surface and this feature sometimes correlates with invasiveness. In contrast, expression of ST3gal6, a member of the sialyltransferase family that sialylates type II lactosamine structures on glycoproteins and glycolipids, was found to be significantly decreased by hypermethylation of the gene in gastrointestinal cancer. At least three isoforms of ST3gal6 are known to exist.

Long Name

ST3 beta-Galactoside alpha-2,3-Sialyltransferase 6

Alternate Names

Sialyltransferase 10, SIAT10, ST3GALVI

Gene Symbol

ST3GAL6

UniProt

NP_006091

Additional ST3GAL6 Products

Product Documents for ST3GAL6 Antibody - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for ST3GAL6 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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