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ST6GALNAC1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-87043

Novus Biologicals, part of Bio-Techne
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NBP1-87043
NBP1-87043-25ul

Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Validated:

Human

Cited:

Human

Applications

Validated:

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin

Cited:

IF/IHC, Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: PQTKPSRHQRTENIKERSLQSLAKPKSQAPTRARRTTIYAEPVPENNALNTQTQPKAHTTGDRGKEANQAPPEEQDKVPHTAQRAAWKSPEKEKTMVNTLSPRGQDAGMASGRTEAQSWKSQDTKTTQGN

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for ST6GALNAC1 Antibody

Immunohistochemistry-Paraffin: ST6GALNAC1 Antibody [NBP1-87043]

Immunohistochemistry-Paraffin: ST6GALNAC1 Antibody [NBP1-87043]

Immunohistochemistry-Paraffin: ST6GALNAC1 Antibody [NBP1-87043] - Analysis in human rectum and skeletal muscle tissues. Corresponding ST6GALNAC1 RNA-seq data are presented for the same tissues.
Immunohistochemistry-Paraffin: ST6GALNAC1 Antibody [NBP1-87043]

Immunohistochemistry-Paraffin: ST6GALNAC1 Antibody [NBP1-87043]

Immunohistochemistry-Paraffin: ST6GALNAC1 Antibody [NBP1-87043] - Staining of human skeletal muscle shows no positivity in myocytes as expected.
Immunohistochemistry-Paraffin: ST6GALNAC1 Antibody [NBP1-87043]

Immunohistochemistry-Paraffin: ST6GALNAC1 Antibody [NBP1-87043]

Immunohistochemistry-Paraffin: ST6GALNAC1 Antibody [NBP1-87043] - Staining of human rectum shows strong positivity in Golgi apparatus in glandular cells.

Applications for ST6GALNAC1 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

Reported in scientific literature (PMID: 30401951)

Immunohistochemistry

1:1000 - 1:2500

Immunohistochemistry-Paraffin

1:1000 - 1:2500
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: ST6 Sialyltransferase 1/ST6GALNAC1

Glycosylation of proteins affects cell-cell interaction, interactions with the matrix, and the functions of intracellular molecules. ST6GALNAC1 transfers a sialic acid, N-acetylneuraminic acid (NeuAc), in an alpha-2,6 linkage to O-linked GalNAc residues. The cancer-associated sialyl-Tn (sTn) antigen is formed by ST6GALNAC1-catalyzed sialylation of GalNAc residues on mucins (Ikehara et al., 1999 [PubMed 10536037]; Sewell et al., 2006 [PubMed 16319059]).[supplied by OMIM]

Long Name

ST6 alpha-N-acetylGalactosaminide alpha-2,6-sialyltransferase 1

Alternate Names

Siat7A, ST6GalNAcI, STYI

Gene Symbol

ST6GALNAC1

Additional ST6 Sialyltransferase 1/ST6GALNAC1 Products

Product Documents for ST6GALNAC1 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for ST6GALNAC1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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