StAR Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-86993

Novus Biologicals, part of Bio-Techne
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NBP1-86993
NBP1-86993-25ul
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Key Product Details

Validated by

Orthogonal Validation, Independent Antibodies

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all StAR Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: QDNGDKVMSKVVPDVGKVFRLEVVVDQPMERLYEELVERMEAMGEWNPNVKEIKVLQKIGKDTFITHELA

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (89%), Rat (86%). Reactivity reported in scientific literature (PMID: 23925558)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for StAR Antibody

Immunohistochemistry-Paraffin: StAR Antibody [NBP1-86993]

Immunohistochemistry-Paraffin: StAR Antibody [NBP1-86993]

Immunohistochemistry-Paraffin: StAR Antibody [NBP1-86993] - Staining of human lymph node.
Immunohistochemistry-Paraffin: StAR Antibody [NBP1-86993]

Immunohistochemistry-Paraffin: StAR Antibody [NBP1-86993]

Immunohistochemistry-Paraffin: StAR Antibody [NBP1-86993] - Staining in human adrenal gland and skeletal muscle tissues.. Corresponding STAR RNA-seq data are presented for the same tissues.
Immunohistochemistry-Paraffin: StAR Antibody [NBP1-86993]

Immunohistochemistry-Paraffin: StAR Antibody [NBP1-86993]

Immunohistochemistry-Paraffin: StAR Antibody [NBP1-86993] - Staining of human testis shows strong positivity in mitochondria in Leydig cells.
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Applications for StAR Antibody

Application
Recommended Usage

Immunohistochemistry

1:200 - 1:500

Immunohistochemistry-Paraffin

1:200 - 1:500
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: StAR

StAR is encoded by this gene plays a key role in the acute regulation of steroid hormone synthesis by enhancing the conversion of cholesterol into pregnenolone. This protein permits the cleavage of cholesterol into pregnenolone by mediating the transport of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane. Mutations in this gene are a cause of congenital lipoid adrenal hyperplasia (CLAH), also called lipoid CAH. A pseudogene of this gene is located on chromosome 13.

Alternate Names

cholesterol trafficker, mitochondrial steroid acute regulatory protein, StAR, StARD1, STARD1StAR-related lipid transfer (START) domain containing 1, START domain containing 1, START domain-containing protein 1, steroid acute regulatory protein, steroidogenic acute regulator, steroidogenic acute regulatory protein, steroidogenic acute regulatory protein, mitochondrial

Gene Symbol

STAR

Additional StAR Products

Product Documents for StAR Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for StAR Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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