STAT2 Antibody (STAT2/2650)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-07617

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 kappa Clone # STAT2/2650

Concentration

0.2 mg/ml

View all STAT2 Antibodies »

Product Summary for STAT2 Antibody (STAT2/2650)

Immunogen

Recombinant full-length human STAT2 protein (Uniprot: P52630)

Localization

Cell surface

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1 kappa

Theoretical MW

113 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Description

200ug/ml of antibody purified from Bioreactor Concentrate by Protein A or G. Prepared in 10 mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0 mg/ml. (NBP3-08587)

Antibody with azide - store at 2 to 8C. Antibody without azide - store at -20 to -80C.

Scientific Data Images for STAT2 Antibody (STAT2/2650)

Immunohistochemistry-Paraffin: STAT2 Antibody (STAT2/2650) [NBP3-07617]

Immunohistochemistry-Paraffin: STAT2 Antibody (STAT2/2650) [NBP3-07617]

Immunohistochemistry-Paraffin: STAT2 Antibody (STAT2/2650) [NBP3-07617] - Formalin-fixed, paraffin-embedded human Prostate Carcinoma stained with STAT2 Mouse Monoclonal Antibody (STAT2/2650).
Immunohistochemistry-Paraffin: STAT2 Antibody (STAT2/2650) [NBP3-07617]

Immunohistochemistry-Paraffin: STAT2 Antibody (STAT2/2650) [NBP3-07617]

Immunohistochemistry-Paraffin: STAT2 Antibody (STAT2/2650) [NBP3-07617] - Formalin-fixed, paraffin-embedded human Prostate Carcinoma stained with STAT2 Mouse Monoclonal Antibody (STAT2/2650).

Applications for STAT2 Antibody (STAT2/2650)

Application
Recommended Usage

Immunohistochemistry-Paraffin

1-2 ug/ml
Application Notes
Immunohistochemistry (Formalin-fixed): 1-2ug/ml for 30 min at RT. Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95C followed by cooling at RT for 20 minutes.
Optimal dilution for a specific application should be determined.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

10 mM PBS with 0.05% BSA

Preservative

0.05% Sodium Azide

Concentration

0.2 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C.

Background: STAT2

Stat-2 is a latent transcription factor that functions both as a signal transducer in the cytoplasm and an activator of transcription in the nucleus. Stat-2 is one of seven members of the Signal transducer and activators of transcription (Stats) family. Stat-2 is phosphorylated at Tyr690 by JAKs(1-3). Additionally, upon activation, Stat-2 will form a multiprotein DNA-binding complex with Stat-1 and ISGF3

Long Name

Signal Transducer and Activator of Transcription 2

Alternate Names

interferon alpha induced transcriptional activator, ISGF-3, MGC59816, p113, signal transducer and activator of transcription 2, signal transducer and activator of transcription 2, 113kD, signal transducer and activator of transcription 2, 113kDa, STAT113

Gene Symbol

STAT2

UniProt

P52630

Additional STAT2 Products

Product Documents for STAT2 Antibody (STAT2/2650)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for STAT2 Antibody (STAT2/2650)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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