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STAT2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-86991

Novus Biologicals, part of Bio-Techne
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NBP1-86991
NBP1-86991-25ul

Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Summary for STAT2 Antibody

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: DPTQLAEMIFNLLLEEKRILIQAQRAQLEQGEPVLETPVESQQHEIESRILDLRAMMEKLVKSISQLKDQQDVFCFRYKIQAKGKTPSLDPHQTKEQKILQETLNELDKRRKEVLDASKALLGRLTTLIELLLPKL

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for STAT2 Antibody

Immunocytochemistry/ Immunofluorescence: STAT2 Antibody [NBP1-86991]

Immunocytochemistry/ Immunofluorescence: STAT2 Antibody [NBP1-86991]

Immunocytochemistry/Immunofluorescence: STAT2 Antibody [NBP1-86991] - Staining of human cell line A-431 shows positivity in plasma membrane and cytoplasm.
STAT2 Antibody

Immunohistochemistry-Paraffin: STAT2 Antibody [NBP1-86991] -

Immunohistochemistry-Paraffin: STAT2 Antibody [NBP1-86991] -Staining of human skin shows moderate cytoplasmic and membranous positivity in squamous epithelial cells.
STAT2 Antibody

Immunohistochemistry-Paraffin: STAT2 Antibody [NBP1-86991] -

Immunohistochemistry-Paraffin: STAT2 Antibody [NBP1-86991] -Staining of human prostate shows moderate cytoplasmic and membranous positivity in glandular cells and smooth muscle cells.

Applications for STAT2 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:200 - 1:500

Immunohistochemistry-Paraffin

1:200 - 1:500
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. ICC/IF,Fixation Permeabilization: Use PFA/Triton X-100.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: STAT2

Stat-2 is a latent transcription factor that functions both as a signal transducer in the cytoplasm and an activator of transcription in the nucleus. Stat-2 is one of seven members of the Signal transducer and activators of transcription (Stats) family. Stat-2 is phosphorylated at Tyr690 by JAKs(1-3). Additionally, upon activation, Stat-2 will form a multiprotein DNA-binding complex with Stat-1 and ISGF3

Long Name

Signal Transducer and Activator of Transcription 2

Alternate Names

interferon alpha induced transcriptional activator, ISGF-3, MGC59816, p113, signal transducer and activator of transcription 2, signal transducer and activator of transcription 2, 113kD, signal transducer and activator of transcription 2, 113kDa, STAT113

Gene Symbol

STAT2

Additional STAT2 Products

Product Documents for STAT2 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for STAT2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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