STAT5a/b Antibody
Novus Biologicals, part of Bio-Techne | Catalog # NBP2-46786
Key Product Details
Species Reactivity
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Predicted:
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Scientific Data Images for STAT5a/b Antibody
Immunohistochemistry: STAT5a/b Antibody [NBP2-46786]
Immunohistochemistry: STAT5a/b Antibody [NBP2-46786] - Staining of human lymph node shows distinct cytoplasmic positivity in subsets of lymphoid cells.Applications for STAT5a/b Antibody
Immunohistochemistry
Immunohistochemistry-Paraffin
Formulation, Preparation, and Storage
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Background: STAT5a/b
Signal transduction and activator of transcription 5 (STAT5) is a member of the Jak/STAT signal transduction pathway and is activated by a variety of cytokines (IL22, IL6, IFN-α). STAT5 has two isoforms (A and B) that share 93% amino acid identity and bind the DNA consensus site TTCN3GAA. STAT5 mediates cytokine signaling by acting as a signal transducer in the cytoplasm and, upon phosphorylation, translocates to the nucleus and activates transcription of specific genes. STAT5 is involved in a wide array of biological processes ranging from regulating apoptosis to adult mammary gland proliferation, differentiation and survival.
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Additional STAT5a/b Products
Product Documents for STAT5a/b Antibody
Product Specific Notices for STAT5a/b Antibody
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.