STEAP3/TSAP6 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-20510

Novus Biologicals, part of Bio-Techne
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NBP2-20510
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all STEAP3/TSAP6 Antibodies »

Product Summary for STEAP3/TSAP6 Antibody

Immunogen

Recombinant protein encompassing a sequence within the center region of human STEAP3/TSAP6. The exact sequence is proprietary.

Reactivity Notes

Mouse (88%), Rat (87%), Bovine (85%).

Localization

Endosome membrane; Multi-pass membrane protein (By similarity)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

55 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for STEAP3/TSAP6 Antibody

STEAP3/TSAP6 Antibody [NBP2-20510] - HepG2 whole cell and cytoplasm extracts (30 ug) were separated by 10% SDS-PAGE, and the membrane was blotted with this antibody diluted at 1:1000. HRP-conjugated anti-rabbit IgG antibody (NBP2-19301) was used to detect the primary antibody.

Applications for STEAP3/TSAP6 Antibody

Application
Recommended Usage

Western Blot

1:500-1:3000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

PBS (pH 7), 20% Glycerol

Preservative

0.025% Proclin 300

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: STEAP3/TSAP6

Endosomal ferrireductase required for efficient transferrin-dependent iron uptake in erythroid cells. Participates in erythroid iron homeostasis by reducing Fe(3+) to Fe(2+). Can also reduce of Cu(2+) to Cu(1+), suggesting that it participates in copper homeostasis. Uses NAD(+) as acceptor (By similarity). May play a role downstream of p53/TP53 to interface apoptosis and cell cycle progression. Indirectly involved in exosome secretion by facilitating the secretion of proteins such as TCTP.

Long Name

Six Transmembrane Epithelial Antigen of the Prostate 3

Alternate Names

AHMIO2, Dudlin-2, pHyde, STMP3, TSAP6

Gene Symbol

STEAP3

UniProt

Q658P3 (Human)

Additional STEAP3/TSAP6 Products

Product Documents for STEAP3/TSAP6 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for STEAP3/TSAP6 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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