STEP Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-81893

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Validated:

Human, Mouse

Applications

ELISA, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1 mg/ml

View all STEP Antibodies »

Product Summary for STEP Antibody - BSA Free

Immunogen

STEP antibody was raised against an 18 amino acid peptide near the amino terminus of human STEP. The immunogen is located within amino acids 180 - 230 of STEP. Amino Acid Squence: LRTPPEPPTPLPPEDRRQ

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

60 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for STEP Antibody - BSA Free

Western Blot: STEP AntibodyBSA Free [NBP2-81893]

Western Blot: STEP AntibodyBSA Free [NBP2-81893]

Western Blot: STEP Antibody [NBP2-81893] - Analysis of STEP in Jurkat cell lysate with STEP antibody at (A) 1 and (B) 2 ug/ml.
Immunocytochemistry/ Immunofluorescence: STEP Antibody - BSA Free [NBP2-81893]

Immunocytochemistry/ Immunofluorescence: STEP Antibody - BSA Free [NBP2-81893]

Immunocytochemistry/Immunofluorescence: STEP Antibody [NBP2-81893] - Analysis of STEP in mouse brain tissue with STEP antibody at 20 ug/ml.
Immunohistochemistry: STEP Antibody - BSA Free [NBP2-81893]

Immunohistochemistry: STEP Antibody - BSA Free [NBP2-81893]

Immunohistochemistry: STEP Antibody [NBP2-81893] - Analysis of STEP in mouse brain tissue with STEP antibody at 5 ug/ml.

Applications for STEP Antibody - BSA Free

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

20 ug/ml

Immunohistochemistry

5 ug/ml

Western Blot

1-2 ug/ml
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Peptide affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: STEP

The protein tyrosine phosphatase non-receptor type 5 or striatum-enriched protein-tyrosine phosphatase (STEP) protein is part of a family of protein tyrosine phosphatases enriched within the CNS, and is a key component of the NMDAR complex. It is expressed within dopaminoceptive neurons in the CNS and particularly enriched within the basal ganglia and related structures. STEP61 is the membrane-associated isoform and STEP46 is the cytosolic protein. In response to transient hypoxia-ischemia in the brain, STEP61 is proteolytically cleaved by calpain, thereby releasing a smaller isoform, STEP33.

Long Name

Tyrosine-protein phosphatase non-receptor type 5

Alternate Names

PTPN5

Gene Symbol

PTPN5

Additional STEP Products

Product Documents for STEP Antibody - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for STEP Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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