STK39 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-30112

Novus Biologicals, part of Bio-Techne
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NBP1-30112
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Immunoprecipitation (Negative), Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

0.2 mg/ml

View all STK39 Antibodies »

Product Summary for STK39 Antibody

Immunogen

maps to a region between residue 425 and 450 of human STE20/SPS1-related proline-alanine-rich protein kinase using the numbering given in entry AAC72238.1

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for STK39 Antibody

Western Blot: STK39 Antibody [NBP1-30112]

Western Blot: STK39 Antibody [NBP1-30112]

Western Blot: STK39 Antibody [NBP1-30112] - Whole cell lysate (5, 15 and 50 ug) from HeLa cells. Antibody used at 0.04 ug/ml.
Immunohistochemistry: STK39 Antibody [NBP1-30112]

Immunohistochemistry: STK39 Antibody [NBP1-30112]

Immunohistochemistry: STK39 Antibody [NBP1-30112] - Sample: FFPE section of human testicular seminoma. Antibody: Affinity purified rabbit anti- SPAK used at a dilution of 1:200 (1ug/ml). Detection: DAB

Applications for STK39 Antibody

Application
Recommended Usage

Immunohistochemistry

1:100 - 1:500

Immunohistochemistry-Paraffin

1:100 - 1:500

Western Blot

1:2000-1:10000
Application Notes
Immunohistochemistry 1:100 - 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

TBS and 0.1% BSA

Preservative

0.09% Sodium Azide

Concentration

0.2 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: STK39

This gene encodes a serine/threonine kinase that is thought to function in the cellular stress response pathway. The kinase is activated in response to hypotonic stress, leading to phosphorylation of several cation-chloride-coupled cotransporters. The catalytically active kinase specifically activates the p38 MAP kinase pathway, and its interaction with p38 decreases upon cellular stress, suggesting that this kinase may serve as an intermediate in the response to cellular stress.

Alternate Names

DCHTsmall intestine SPAK-like kinase, DKFZp686K05124, EC 2.7.11, EC 2.7.11.1, PASK, proline-alanine-rich STE20-related kinase, serine threonine kinase 39, Serine/threonine-protein kinase 39, SPAKserine threonine kinase 39 (STE20/SPS1 homolog, yeast), STE20/SPS1 homolog, STE20/SPS1-related proline-alanine-rich protein kinase, Ste20-like protein kinase, Ste-20-related kinase

Gene Symbol

STK39

Additional STK39 Products

Product Documents for STK39 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for STK39 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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