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Synapsin II Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NB120-13258

Novus Biologicals, part of Bio-Techne
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NB120-13258
NB120-13258-0.025mg

Key Product Details

Species Reactivity

Mouse, Rat

Applications

Immunoprecipitation, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

Synthetic peptide corresponding to a portion of rat Synapsin II. The sequence is completely conserved in mouse.

Localization

Synapse

Specificity

This detects ~74 and ~54 kDa proteins, corresponding to the apparent molecular masses of synapsin IIa and IIb on SDS-PAGE immunoblots, in samples from mouse and rat origins.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Applications for Synapsin II Antibody

Application
Recommended Usage

Immunoprecipitation

1:100

Western Blot

1:100-1:2000
Application Notes
WB: Use at a dilution of 1/5000. This dilution was sufficient for detection of Synapsin II in 15 ug of rat brain tissue extract. Detects bands of approximately 74 and 54 kDa, corresponding to the apparent molecular masses of synapsin IIa and IIb.(predicted molecular weight: 57.5 kDa). Not tested in other applications.Optimal dilutions/concentrations should be determined by the end user.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS (pH 7.2) and 50% Glycerol

Preservative

0.09% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Synapsin II

Synapsin II is a member of the synapsin gene family. Synapsins are neuronal phosphoproteins which associate with the cytoplasmic surface of synaptic vesicles. Family members are characterized by common protein domains, and they are implicated in synaptogenesis and the modulation of neurotransmitter release, suggesting a potential role in several neuropsychiatric diseases. This member of the synapsin family is a neuron-specific phosphoprotein that selectively binds to small synaptic vesicles in the presynaptic nerve terminal.

Alternate Names

synapsin IISYNII, synapsin-2, SYNIIa, SYNIIb

Entrez Gene IDs

6854 (Human); 29179 (Rat)

Gene Symbol

SYN2

Additional Synapsin II Products

Product Documents for Synapsin II Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Synapsin II Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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