Synaptophysin Antibody (SP11)
Novus Biologicals, part of Bio-Techne | Catalog # NB120-16659
Recombinant Monoclonal Antibody
Key Product Details
Species Reactivity
Validated:
Human, Mouse
Cited:
Human, Mouse
Applications
Validated:
Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin
Cited:
Immunocytochemistry/ Immunofluorescence, Immunohistochemistry-Paraffin
Label
Unconjugated
Antibody Source
Monoclonal Rabbit IgG Clone # SP11
Concentration
This product is unpurified. The exact concentration of antibody is not quantifiable.
Product Specifications
Immunogen
Synthetic peptide of human Synaptophysin.
Reactivity Notes
Mouse reactivity reported in scientific literature (PMID: 29420126). Not yet tested in other species.
Localization
Cytoplasmic
Specificity
This antibody recognizes a protein of 38kDa, identified as synaptophysin. It labels normal neuroendocrine cells of human adrenal medulla, carotid body, skin, pituitary gland, thyroid, lung, pancreas, gastrointestinal mucosa, Paneth's cells in the gastrointestinal tract and gastric parietal cells. Neurons in the brain, spinal cord, and retina are also labeled. In combination with anti-chromogranin A and anti-NSE, anti-synaptophysin is very useful in the identification of normal neuroendocrine cells and neuroendocrine neoplasms.
Marker
Pre-synaptic marker
Clonality
Monoclonal
Host
Rabbit
Isotype
IgG
Theoretical MW
38 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Scientific Data Images for Synaptophysin Antibody (SP11)
Immunohistochemistry-Paraffin: Synaptophysin Antibody (SP11) [NB120-16659]
Immunohistochemistry-Paraffin: Synaptophysin Antibody (SP11) [NB120-16659] - Formalin fixed paraffin embedded human pancreas stained with Synaptophysin antibody (NB120-16659).Applications for Synaptophysin Antibody (SP11)
Application
Recommended Usage
Immunohistochemistry
1:25-1:50
Immunohistochemistry-Paraffin
1:25-1:50
Application Notes
IHC-P: recommended incubation time of 30-60 min at RT. Use in Immunocytochemistry/immunofluorescence reported in scientific literature (PMID 25483960).
Formulation, Preparation, and Storage
Purification
Tissue culture supernatant
Formulation
Tissue culture supernatant
Preservative
0.05% Sodium Azide
Concentration
This product is unpurified. The exact concentration of antibody is not quantifiable.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store at 4C.
Background: Synaptophysin
Alternate Names
SYP
Gene Symbol
SYP
Additional Synaptophysin Products
Product Documents for Synaptophysin Antibody (SP11)
Product Specific Notices for Synaptophysin Antibody (SP11)
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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