Synaptophysin Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-88112

Novus Biologicals, part of Bio-Techne
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NBP1-88112
NBP1-88112-25ul
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Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Synaptophysin Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: DMDVVNQLVAGGQFRVVKEPLGFVKVLQWAAPSVL

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (83%).

Marker

Pre-synaptic marker

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Synaptophysin Antibody

Western Blot: Synaptophysin Antibody [NBP1-88112]

Western Blot: Synaptophysin Antibody [NBP1-88112]

Western Blot: Synaptophysin Antibody [NBP1-88112] - Analysis in human cerebral cortex tissue.
Immunohistochemistry-Paraffin: Synaptophysin Antibody [NBP1-88112]

Immunohistochemistry-Paraffin: Synaptophysin Antibody [NBP1-88112]

Immunohistochemistry-Paraffin: Synaptophysin Antibody [NBP1-88112] - Staining in human cerebral cortex and liver tissues . Corresponding SYP RNA-seq data are presented for the same tissues.
Immunohistochemistry-Paraffin: Synaptophysin Antibody [NBP1-88112]

Immunohistochemistry-Paraffin: Synaptophysin Antibody [NBP1-88112]

Immunohistochemistry-Paraffin: Synaptophysin Antibody [NBP1-88112] - Staining of human cerebral cortex shows strong positivity in neuropil.
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Applications for Synaptophysin Antibody

Application
Recommended Usage

Immunohistochemistry

1:200 - 1:500

Immunohistochemistry-Paraffin

1:200 - 1:500

Western Blot

0.04-0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Synaptophysin

Synaptophysin (Syp I), also called the major synaptic vesicle protein p38, is an integral membrane glycoprotein found in the synaptic vesicles of brain, neuron and neuroendocrine cells. Synaptophysin is one of the most abundant membrane proteins, comprising approximately 7% of the total protein in small synaptic vesicles. In mature nerve terminals it forms a complex with the vesicular membrane protein synaptobrevin, which appears to modulate synaptobrevin's interaction with the plasma membrane-associated proteins syntaxin and SNAP25 to form the SNARE complex as a prerequisite for membrane fusion. Synaptophysin may also be used as a neuroendocrine tumor marker in both neuroscience and cancer research.

Alternate Names

SYP

Gene Symbol

SYP

Additional Synaptophysin Products

Product Documents for Synaptophysin Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Synaptophysin Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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