Synaptotagmin 1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-87362

Novus Biologicals, part of Bio-Techne
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NBP1-87362
NBP1-87362-25ul
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Key Product Details

Validated by

Independent Antibodies

Species Reactivity

Validated:

Human

Predicted:

Mouse (100%), Rat (100%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Synaptotagmin-1 Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: GGKNAINMKDVKDLGKTMKDQALKDDDAETGLTDGEEKEEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQ

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Synaptotagmin 1 Antibody

Western Blot: Synaptotagmin 1 Antibody [NBP1-87362]

Western Blot: Synaptotagmin 1 Antibody [NBP1-87362]

Western Blot: Synaptotagmin 1 Antibody [NBP1-87362] - Analysis in human cerebral cortex tissue.
Immunohistochemistry-Paraffin: Synaptotagmin 1 Antibody [NBP1-87362]

Immunohistochemistry-Paraffin: Synaptotagmin 1 Antibody [NBP1-87362]

Immunohistochemistry-Paraffin: Synaptotagmin 1 Antibody [NBP1-87362] - Analysis in human cerebral cortex and pancreas tissues using NBP1-87362 antibody. Corresponding Synaptotagmin 1 RNA-seq data are presented for the same tissues.
Synaptotagmin 1 Antibody Immunohistochemistry-Paraffin: Synaptotagmin 1 Antibody Antibody [NBP1-87362]

Immunohistochemistry-Paraffin: Synaptotagmin 1 Antibody Antibody [NBP1-87362]

Staining of human cerebellum, liver, pancreas and testis using NBP1-87362 (A) shows similar protein distribution across tissues to independent antibody NBP2-34215 (B).

Applications for Synaptotagmin 1 Antibody

Application
Recommended Usage

Immunohistochemistry

1:20 - 1:50

Immunohistochemistry-Paraffin

1:20 - 1:50

Western Blot

0.04 - 0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Synaptotagmin-1

Synaptotagmin is widely regarded as the primary calcium sensor for synaptic vesicle exocytosis (Fernandez-Chacon et al., 2001; Wang et al., 2003). Moreover recent studies indicate that the protein also plays a key role in endocytosis (Poskanzer et al., 2003). Synaptotagmin can be phosphorylated by multiple protein kinases and this may play a key role in modulation of synaptotagmin ability to influence both the exocytotic and endocytotic components of synaptic transmission (Hilfiker et al., 1999; Lee et al., 2004).

Alternate Names

P65, SVP65, Synaptotagmin1, SYT1

Gene Symbol

SYT1

Additional Synaptotagmin-1 Products

Product Documents for Synaptotagmin 1 Antibody

Product Datasheets

Certificate of Analysis

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Product Specific Notices for Synaptotagmin 1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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