SynGAP Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-13035

Novus Biologicals, part of Bio-Techne
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NBP3-13035
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Key Product Details

Species Reactivity

Validated:

Mouse, Rat

Applications

Immunocytochemistry/ Immunofluorescence, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all SynGAP Antibodies »

Product Summary for SynGAP Antibody

Immunogen

Recombinant protein encompassing a sequence within the center region of human SynGAP. The exact sequence is proprietary.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

Centrifuge briefly prior to opening.

Scientific Data Images for SynGAP Antibody

Immunocytochemistry/ Immunofluorescence: SynGAP Antibody [NBP3-13035]

Immunocytochemistry/ Immunofluorescence: SynGAP Antibody [NBP3-13035]

Immunocytochemistry/Immunofluorescence: SynGAP Antibody [NBP3-13035] - SynGAP antibody detects SynGAP protein at Synapse by immunofluorescent analysis. Sample: DIV10 rat hippocampal neuron cells were fixed in 4% paraformaldehyde at RT for 15 min. Green: SynGAP stained by SynGAP antibody (NBP3-13035) diluted at 1:500. Red: Tau, a marker, stained by Tau antibody [GT287] diluted at 1:500.
SynGAP Antibody

Western Blot: SynGAP Antibody [NBP3-13035] -

Western Blot: SynGAP Antibody [NBP3-13035] - Various tissue extracts (50 ug) were separated by 5% SDS-PAGE, and the membrane was blotted with SynGAP antibody (NBP3-13035) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody was used to detect the primary antibody.

Applications for SynGAP Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

PBS (pH 7), 20% Glycerol

Preservative

0.025% Proclin 300

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: SynGAP

Synaptic Ras GTPase Activating Protein (SynGAP) is a PDZ-domain interacting protein expressed almost exclusively in the brain. SynGAP has been shown to be a major component of postsynaptic density and associates with post synaptic density 95 kDa (PSD-95), a synaptic scaffold protein, and synaptic N-methyl-D-aspartate (NMDA) receptors. SynGAP Ras-GTPase activity has also been shown to be inhibited by phosphorylation by CaM kinase II, another abundant protein located in the postsynaptic density. It has been proposed that SynGAP may function as a negative regulator of MAP Kinase activation in the absence of active NMDA receptors.

Alternate Names

DKFZp761G1421, KIAA1938135kDa, MRD5, synaptic Ras GTPase activating protein 1, synaptic Ras GTPase activating protein 1 homolog (rat), Synaptic Ras-GAP 1

Gene Symbol

SYNGAP1

Additional SynGAP Products

Product Documents for SynGAP Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for SynGAP Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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