Synphilin-1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-06159

Novus Biologicals, part of Bio-Techne
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NBP3-06159-100ul
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all Synphilin-1 Antibodies »

Product Summary for Synphilin-1 Antibody

Immunogen

Produced in rabbits immunized with E. coli-derived Human Synphilin-1 fragment.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

This antibody can be stored at 2C-8C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20C to -80C. Avoid repeated freeze-thaw cycles.

Scientific Data Images for Synphilin-1 Antibody

Immunohistochemistry-Paraffin: Synphilin-1 Antibody [NBP3-06159]

Immunohistochemistry-Paraffin: Synphilin-1 Antibody [NBP3-06159]

Immunohistochemistry-Paraffin: Synphilin-1 Antibody [NBP3-06159] - Immunochemical staining of human Synphilin-1 Antibody in human brain with rabbit polyclonal antibody at 1:100 dilution, formalin-fixed paraffin embedded sections.
Immunohistochemistry-Paraffin: Synphilin-1 Antibody [NBP3-06159]

Immunohistochemistry-Paraffin: Synphilin-1 Antibody [NBP3-06159]

Immunohistochemistry-Paraffin: Synphilin-1 Antibody [NBP3-06159] - Immunochemical staining of human Synphilin-1 Antibody in human kidney with rabbit polyclonal antibody at 1:100 dilution, formalin-fixed paraffin embedded sections.

Applications for Synphilin-1 Antibody

Application
Recommended Usage

Immunohistochemistry-Paraffin

1:50-1:200
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Antigen and protein A Affinity-purified

Formulation

PBS

Preservative

0.03% Proclin 300

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Synphilin-1

Synuclein alpha interacting protein (Synphilin-1) contains several protein-protein interaction domains and interacts with alpha synuclein in neurons. Mutations of SNCAIP have been linked to Parkinson disease. The amino acid sequence of synphilin-1 shares a high level of identity with its human counterpart, particularly in regions containing ankyrin-like motifs and the coiled-coil domain. Expression pattern of synphilin-1 in tissues is similar in both mouse and human. Synphilin-1 has an important role in the formation of aggregates and cytotoxicity in Parkinson disease and also Dorfin may be involved in the pathogenic process by ubiquitylation of synphilin-1.

Alternate Names

Alpha-synuclein-interacting protein, MGC39814, Sph1, synphilin-1, synuclein, alpha interacting protein, SYPH1

Gene Symbol

SNCAIP

Additional Synphilin-1 Products

Product Documents for Synphilin-1 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Synphilin-1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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