Syntaxin 1A Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-56031

Novus Biologicals, part of Bio-Techne
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NBP2-56031
NBP2-56031-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (100%), Rat (100%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Syntaxin 1A Antibodies »

Product Summary for Syntaxin 1A Antibody

Immunogen

This antibody was developed against a recombinant protein corresponding to the following amino acid sequence: QRQLEITGRTTTSEELEDMLESGNPAIF

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Syntaxin 1A Antibody

Immunohistochemistry-Paraffin: Syntaxin 1A Antibody [NBP2-56031]

Immunohistochemistry-Paraffin: Syntaxin 1A Antibody [NBP2-56031]

Immunohistochemistry-Paraffin: Syntaxin 1A Antibody [NBP2-56031] - Immunohistochemical staining of human cerebral cortex shows strong cytoplasmic positivity in neuropil.

Applications for Syntaxin 1A Antibody

Application
Recommended Usage

Immunohistochemistry

1:1000 - 1:2500

Immunohistochemistry-Paraffin

1:1000 - 1:2500
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Syntaxin 1A

Synaptic vesicles store neurotransmitters that are released during calcium-regulated exocytosis. The specificity of neurotransmitter release requires the localization of both synaptic vesicles and calcium channels to the presynaptic active zone. Syntaxins function in this vesicle fusion process. Syntaxins also serve as a substrate for botulinum neurotoxin type C, a metalloprotease that blocks exocytosis and has high affinity for a molecular complex that includes the alpha-latrotoxin receptor (MIM 600565) which produces explosive exocytosis (Zhang et al., 1995 [PubMed 7622072]).[supplied by OMIM]

Alternate Names

Brain Syntaxin, HPC-1, p35-1, STX1A, SYN1A

Gene Symbol

STX1A

Additional Syntaxin 1A Products

Product Documents for Syntaxin 1A Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Syntaxin 1A Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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