Syntaxin Binding Protein 4 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-92471

Novus Biologicals, part of Bio-Techne
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NBP1-92471
NBP1-92471-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Syntaxin Binding Protein 4 Antibodies »

Product Summary for Syntaxin Binding Protein 4 Antibody

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: TPLGRNGRSIPATLALESKELVKSVRALLDMDCLPYGWEEAYTADGIKYFINHVTQTTSWIHPVMSVLNLSRSEENEEDCSRELPNQK

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (83%), Rat (81%)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Syntaxin Binding Protein 4 Antibody

Western Blot: Syntaxin Binding Protein 4 Antibody [NBP1-92471]

Western Blot: Syntaxin Binding Protein 4 Antibody [NBP1-92471]

Western Blot: Syntaxin Binding Protein 4 Antibody [NBP1-92471] - Lane 1: Marker [kDa] 250, 130, 100, 70, 55, 35, 25, 15, 10. Lane 2: Tonsil
Immunohistochemistry-Paraffin: Syntaxin Binding Protein 4 Antibody [NBP1-92471]

Immunohistochemistry-Paraffin: Syntaxin Binding Protein 4 Antibody [NBP1-92471]

Immunohistochemistry-Paraffin: Syntaxin Binding Protein 4 Antibody [NBP1-92471] - Staining of human testis shows strong cytoplasmic positivity in cells in seminiferous ducts.

Applications for Syntaxin Binding Protein 4 Antibody

Application
Recommended Usage

Immunohistochemistry

1:200 - 1:500

Immunohistochemistry-Paraffin

1:200 - 1:500

Western Blot

0.04-0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Syntaxin Binding Protein 4

Synip (Syntaxin 4-Interacting protein) specifically binds to Syntaxin 4 and is uniquely expressed in muscle and adipose tissue. The binding interaction of Synip with syntaxin 4 is regulated by insulin, which also induces dissociation of the Synip-syntaxin 4 complex. Synip plays a role in the translocation of transport vesicles from the cytoplasm to the plasma membrane and functions as a positive regulator of insulin-stimulated GLUT4 translocation. Synip also competes with VAMP2 but Not SNAP23 for binding to Syntaxin 4 (1-3).

Alternate Names

FLJ16496, MGC50337, STX4-interacting protein, SynipMGC149829, syntaxin 4 interacting protein, Syntaxin 4-interacting protein, syntaxin binding protein 4, syntaxin-binding protein 4

Gene Symbol

STXBP4

Additional Syntaxin Binding Protein 4 Products

Product Documents for Syntaxin Binding Protein 4 Antibody

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Certificate of Analysis

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Product Specific Notices for Syntaxin Binding Protein 4 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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