SYT17 Antibody - Azide and BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-03494

Novus Biologicals, part of Bio-Techne
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NBP1-03494-0.1mg
NBP1-03494
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Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

Immunohistochemistry, Immunohistochemistry-Frozen, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

Azide and BSA Free

Concentration

LYOPH mg/ml

View all SYT17 Antibodies »

Product Specifications

Immunogen

A synthetic peptide from the internal region of human SYT17 conjugated to an immunogenic carrier protein was used as the antigen. The peptide is homologous in rat and mouse.

Reactivity Notes

The antigen is homologous in Mouse and Rat.

Localization

Subcellular location: membrane; peripheral membrane protein.; tissue specificity: expressed abundantly in brain (frontal and temporal lobes, hippocampus, hypothalamus, amygdala, substantia nigra, and pituitary), kidney, and prostate. expressed in fetal br

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for SYT17 Antibody - Azide and BSA Free

Immunohistochemistry: SYT17 Antibody - Azide and BSA Free [NBP1-03494]

Immunohistochemistry: SYT17 Antibody - Azide and BSA Free [NBP1-03494]

Immunohistochemistry: SYT17 Antibody [NBP1-03494] - IHC on mouse brain (cryo section) using Rabbit antibody to internal region of Synaptotagmin 17 (SYT17): IgG at a concentration of 50 ug/ml incubated overnight at 4C.
Immunohistochemistry: SYT17 Antibody - Azide and BSA Free [NBP1-03494]

Immunohistochemistry: SYT17 Antibody - Azide and BSA Free [NBP1-03494]

Immunohistochemistry: SYT17 Antibody [NBP1-03494] - IHC on mouse brain (cryo section) using Rabbit antibody to internal region of Synaptotagmin 17 (SYT17): IgG at a concentration of 50 ug/ml incubated overnight at 4C.
Immunohistochemistry: SYT17 Antibody - Azide and BSA Free [NBP1-03494]

Immunohistochemistry: SYT17 Antibody - Azide and BSA Free [NBP1-03494]

Immunohistochemistry: SYT17 Antibody [NBP1-03494] - IHC on mouse brain (cryo section) using Rabbit antibody to internal region of Synaptotagmin 17 (SYT17): IgG at a concentration of 50 ug/ml incubated overnight at 4C.
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Applications for SYT17 Antibody - Azide and BSA Free

Application
Recommended Usage

Immunohistochemistry

10-50 ug/ml

Immunohistochemistry-Frozen

10-50 ug/ml

Western Blot

10-50 ug/ml

Formulation, Preparation, and Storage

Purification

Ammonium sulfate precipitation

Reconstitution

Reconstitute 0.5 mg size in 0.5 ml of sterile water. Centrifuge to remove any insoluble material. Glycerol may be added (1:1) for additional stability. Please note the 0.1 mg size is provided in reconstituted format.

Formulation

Lyophilized from PBS

Format

Azide and BSA Free

Preservative

No Preservative

Concentration

LYOPH mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: SYT17

The synaptotagmins are integral membrane proteins of synaptic vesicles thought to serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis. Calcium binding to synaptotagmin participates in triggering neurotransmitter release at the synapse. The first C2 domain mediates Ca(2+)-dependent phospholipid binding. The second C2 domain mediates interaction with Stonin 2. Synaptotagmin may have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone. A Ca(2+)-dependent interaction between synaptotagmin and putative receptors for activated protein kinase C has also been reported. It can bind to at least three additional proteins in a Ca(2+)-independent manner; these are neurexins, syntaxin and AP2.

Alternate Names

B/K protein, synaptotagmin XVIIProtein B/K, synaptotagmin-17, sytXVII

Entrez Gene IDs

51760 (Human); 110058 (Mouse); 192189 (Rat)

Gene Symbol

SYT17

UniProt

Q9BSW7 (Human), Q920M7 (Mouse), Q62807 (Rat)

Additional SYT17 Products

Product Documents for SYT17 Antibody - Azide and BSA Free

Product Datasheets

Certificate of Analysis

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Product Specific Notices for SYT17 Antibody - Azide and BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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