TAB1 Antibody (2W0P2)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-16167

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-16167-100ul
NBP3-16167-20ul
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Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Applications

Immunocytochemistry/ Immunofluorescence, Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # 2W0P2

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all TAB1 Antibodies »

Product Summary for TAB1 Antibody (2W0P2)

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 405-504 of human TAB1 (Q15750). VTLSLVMPSQGQMVNGAHSASTLDEATPTLTNQSPTLTLQSTNTHTQSSSSSSDGGLFRSRPAHSLPPGEDGRVEPYVDFAEFYRLWSVDHGEQSVVTAP

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for TAB1 Antibody (2W0P2)

Western Blot: TAB1 Antibody (2W0P2) [NBP3-16167]

Western Blot: TAB1 Antibody (2W0P2) [NBP3-16167]

Western Blot: TAB1 Antibody (2W0P2) [NBP3-16167] - Western blot analysis of extracts of various cell lines, using TAB1 Rabbit mAb (NBP3-16167) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.
Immunocytochemistry/ Immunofluorescence: TAB1 Antibody (2W0P2) [NBP3-16167]

Immunocytochemistry/ Immunofluorescence: TAB1 Antibody (2W0P2) [NBP3-16167]

Immunocytochemistry/Immunofluorescence: TAB1 Antibody (2W0P2) [NBP3-16167] - Immunofluorescence analysis of U-2 OS cells using TAB1 Rabbit mAb (NBP3-16167) at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining.

Applications for TAB1 Antibody (2W0P2)

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:50 - 1:200

Western Blot

1:500 - 1:1000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, 0.05% BSA, 50% glycerol, pH7.3

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: TAB1

TAB1, TAK1 binding protein, enhances activity of the plasminogen activator inhibitor 1 gene promoter, which is regulated by TGF-beta, and increases the kinase activity of TAK1. TAB1 may function as an activator of the TAK1 MAPKKK in TGF-beta signal transduction (1). Findings suggest that alternative activation pathways contribute to the biological responses of p38alpha to various stimuli. Interaction of p38alpha with TAB1 leads to autophosphorylation and activation of p38alpha (2).

Long Name

TAK1-binding Protein

Alternate Names

MAP3K7IP1

Gene Symbol

TAB1

Additional TAB1 Products

Product Documents for TAB1 Antibody (2W0P2)

Product Datasheets

Certificate of Analysis

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Product Specific Notices for TAB1 Antibody (2W0P2)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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