TAB1 Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-76595

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Human, Mouse

Applications

ELISA, Immunocytochemistry/ Immunofluorescence, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1 mg/ml

View all TAB1 Antibodies »

Product Specifications

Immunogen

Antibody was raised against a synthetic peptide corresponding to 13 amino acids in the center of human TAB1. The immunogen is located within amino acids 220 - 270 of TAB1. Amino Acid Squence: ESTRRIGDYKVKY

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for TAB1 Antibody - BSA Free

Western Blot: TAB1 AntibodyBSA Free [NBP1-76595]

Western Blot: TAB1 AntibodyBSA Free [NBP1-76595]

Western Blot: TAB1 Antibody [NBP1-76595] - 3T3 cell lysate with TAB1 antibody at (A) 0.5, (B) 1, and (C) 2 ug/ml.
Immunocytochemistry/ Immunofluorescence: TAB1 Antibody - BSA Free [NBP1-76595]

Immunocytochemistry/ Immunofluorescence: TAB1 Antibody - BSA Free [NBP1-76595]

Immunocytochemistry/Immunofluorescence: TAB1 Antibody [NBP1-76595] - Immunofluorescence of TAB1 in 3T3 cells with TAB1 antibody at 2 ug/mL.
Immunocytochemistry/ Immunofluorescence: TAB1 Antibody - BSA Free [NBP1-76595]

Immunocytochemistry/ Immunofluorescence: TAB1 Antibody - BSA Free [NBP1-76595]

Immunocytochemistry/Immunofluorescence: TAB1 Antibody [NBP1-76595] - K562 cells with TAB1 antibody at 1 ug/ml.

Applications for TAB1 Antibody - BSA Free

Application
Recommended Usage

ELISA

1:100-1:2000

Immunocytochemistry/ Immunofluorescence

1-2 ug/ml

Western Blot

0.5-2 ug/ml
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Peptide affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: TAB1

TAB1 was identified as a regulator of the MAP kinase kinase kinase TAK1/MAP3K7, which is known to mediate various intracellular signaling pathways, such as those induced by TGF-beta and members of the Toll-IL-1R (TIR) superfamily, thus acting as an intermediate in both proliferative and innate and adaptive immune responses. This protein, together with either TAB2 or TAB3, activates TAK1 kinase in response to upstream signals. It has been shown that the C-terminal portion of TAB1 is sufficient for binding and activation of TAK1, while a portion of the N-terminus acts as a dominant-negative inhibitor of TGF-beta, demonstrating how this protein can function as a mediator between TGF-beta receptors and TAK1.

Long Name

TAK1-binding Protein

Alternate Names

MAP3K7IP1

Gene Symbol

TAB1

UniProt

NP_006107 (Human)

Additional TAB1 Products

Product Documents for TAB1 Antibody - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for TAB1 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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