TACE/ADAM17 Antibody (MM0561-8C13) - Azide and BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-12018

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Validated:

Human

Cited:

Human

Applications

Validated:

CyTOF-ready, Flow Cytometry, Western Blot

Cited:

Flow Cytometry

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # MM0561-8C13

Format

Azide and BSA Free

Concentration

LYOPH mg/ml

View all TACE/ADAM17 Antibodies »

Product Specifications

Immunogen

Human recombinant TACE/ADAM17

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Scientific Data Images for TACE/ADAM17 Antibody (MM0561-8C13) - Azide and BSA Free

Flow Cytometry: TACE/ADAM17 Antibody (MM0561-8C13) - Azide and BSA Free [NBP2-12018]

Flow Cytometry: TACE/ADAM17 Antibody (MM0561-8C13) - Azide and BSA Free [NBP2-12018]

Flow Cytometry: TACE/ADAM17 Antibody (MM0561-8C13) [NBP2-12018] - Analysis of the AF647 conjugate of this antibody. A cell surface stain was performed on THP-1 cells with TACE/ADAM17 antibody NBP2-12018AF647 (blue) along with a matched isotype control NBP2-27287AF647 (orange). Cells were incubated in an antibody dilution of 2 ug/mL for 20 minutes at RT.
Flow Cytometry: TACE/ADAM17 Antibody (MM0561-8C13) - Azide and BSA Free [NBP2-12018]

Flow Cytometry: TACE/ADAM17 Antibody (MM0561-8C13) - Azide and BSA Free [NBP2-12018]

Flow Cytometry: TACE/ADAM17 Antibody (MM0561-8C13) [NBP2-12018] - A cell surface stain was performed on THP-1 cells with TACE/ADAM17 antibody NBP2-12018 (blue) along with a matched isotype control NBP2-27287 (orange). Cells were incubated in an antibody dilution of 1 ug/mL for 20 minutes at RT followed by anti-mouse conjugated to Dylight 488 secondary.

Applications for TACE/ADAM17 Antibody (MM0561-8C13) - Azide and BSA Free

Application
Recommended Usage

Flow Cytometry

1:20-1:100

Western Blot

1:500-1:1000
Application Notes
This antibody is Cytof ready.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein G purified

Reconstitution

Reconstitute with sterilized PBS to a final concentration of 0.5 mg/ml.

Formulation

Lyophilized from a 0.2 um filtered solution in PBS. 0.025 mg size is provided in liquid form, PBS

Format

Azide and BSA Free

Preservative

No Preservative

Concentration

LYOPH mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: TACE/ADAM17

ADAM17 encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biologic processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene functions as a tumor necrosis factor-alpha converting enzyme; binds mitotic arrest deficient 2 protein; and also plays a prominent role in the activation of the Notch signaling pathway.

Long Name

TNF-alpha Converting Enzyme

Alternate Names

ADAM17, CD156b

Gene Symbol

ADAM17

UniProt

P78536

Additional TACE/ADAM17 Products

Product Documents for TACE/ADAM17 Antibody (MM0561-8C13) - Azide and BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for TACE/ADAM17 Antibody (MM0561-8C13) - Azide and BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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