TAO Kinase 1 Antibody (SR1074)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-22597

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-22597-100ul
NBP3-22597-50ul
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Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # SR1074

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all TAO Kinase 1 Antibodies »

Product Specifications

Immunogen

A synthesized peptide derived from human TAO Kinase 1 (Uniprot #: Q7L7X3)

Specificity

Detects endogenous levels of total TAO Kinase 1

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

116 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for TAO Kinase 1 Antibody (SR1074)

Western Blot: TAO Kinase 1 Antibody (SR1074) [NBP3-22597] -

Western Blot: TAO Kinase 1 Antibody (SR1074) [NBP3-22597] - Western blot analysis using NBP3-22597 in (1) HeLa cell lysate; (2) RAW 264.7 cell lysate; (3) C6 cell lysate.

Applications for TAO Kinase 1 Antibody (SR1074)

Application
Recommended Usage

Western Blot

1:500-1:2000

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, pH 7.4, 150mM NaCl, 50% glycerol.

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: TAO Kinase 1

TAOK1, a member of the Ste20 kinase family, is a TAO type protein kinase that acts as an upstream activator to MARK by phosphorylation. When activated, MARK enhances microtubule dynamics and leads to phosphorylation and detachment of tau or equivalent MAPs from microtubules. Overexpression of MARK eventually leads to microtubule breakdown and cell death, but in neuronal cells the primary effect is to allow the development of neurites during differentiation.

Long Name

Serine/threonine-protein kinase TAO1

Alternate Names

hKFC-B, hTAOK1, KIAA1361, MAP3K16, MARK Kinase, MARKK, PSK-2, PSK2, TAOK1

Gene Symbol

TAOK1

Additional TAO Kinase 1 Products

Product Documents for TAO Kinase 1 Antibody (SR1074)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for TAO Kinase 1 Antibody (SR1074)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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