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TAO Kinase 1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-89864

Novus Biologicals, part of Bio-Techne
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NBP1-89864
NBP1-89864-25ul

Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (98%), Rat (96%). Backed by our 100% Guarantee.

Applications

ELISA, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: LSPEAFSHSYPGASGWSHNPTGGPGPHWGHPMGGPPQAWGHPMQGGPQPWGHPSGPMQGVPRGSSMGVRNSPQALRRTASGGRTEQGMSRSTSVTSQISNGSH

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for TAO Kinase 1 Antibody

Immunocytochemistry/ Immunofluorescence: TAO Kinase 1 Antibody [NBP1-89864]

Immunocytochemistry/ Immunofluorescence: TAO Kinase 1 Antibody [NBP1-89864]

Immunocytochemistry/Immunofluorescence: TAO Kinase 1 Antibody [NBP1-89864] - TAO1 staining in human SH-SY5Y cell line. ICC/IF image submitted by a verified customer review.
Immunohistochemistry-Paraffin: TAO Kinase 1 Antibody [NBP1-89864]

Immunohistochemistry-Paraffin: TAO Kinase 1 Antibody [NBP1-89864]

Immunohistochemistry-Paraffin: TAO Kinase 1 Antibody [NBP1-89864] - Staining of human liver shows strong cytoplasmic positivity in hepatocytes.
Immunocytochemistry/ Immunofluorescence: TAO Kinase 1 Antibody [NBP1-89864]

Immunocytochemistry/ Immunofluorescence: TAO Kinase 1 Antibody [NBP1-89864]

Immunocytochemistry/Immunofluorescence: TAO Kinase 1 Antibody [NBP1-89864] - Staining of human cell line A-431 shows localization to vesicles.

Applications for TAO Kinase 1 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25 - 2 ug/mL

Immunohistochemistry

1:20 - 1:50

Immunohistochemistry-Paraffin

1:20 - 1:50
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. ICC/IF Fixation/Permeabilization: PFA/Triton X-100. This TAO Kinase 1 Antibody is validated for ELISA from a verified customer review.

Reviewed Applications

Read 2 reviews rated 5 using NBP1-89864 in the following applications:

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2), 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: TAO Kinase 1

TAOK1, a member of the Ste20 kinase family, is a TAO type protein kinase that acts as an upstream activator to MARK by phosphorylation. When activated, MARK enhances microtubule dynamics and leads to phosphorylation and detachment of tau or equivalent MAPs from microtubules. Overexpression of MARK eventually leads to microtubule breakdown and cell death, but in neuronal cells the primary effect is to allow the development of neurites during differentiation.

Long Name

Serine/threonine-protein kinase TAO1

Alternate Names

hKFC-B, hTAOK1, KIAA1361, MAP3K16, MARK Kinase, MARKK, PSK-2, PSK2, TAOK1

Gene Symbol

TAOK1

Additional TAO Kinase 1 Products

Product Documents for TAO Kinase 1 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for TAO Kinase 1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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