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TARBP1 Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-76400

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Validated:

Human, Mouse

Applications

ELISA, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1 mg/ml

Product Summary for TARBP1 Antibody - BSA Free

Immunogen

Antibody was raised against a 17 amino acid synthetic peptide from near the center of human TRBP1. The immunogen is located within amino acids 1310 - 1360 of TRBP1. Amino Acid Squence: HGAGNAKKNWQRIQEHF

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

182 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for TARBP1 Antibody - BSA Free

Western Blot: TARBP1 AntibodyBSA Free [NBP1-76400]

Western Blot: TARBP1 AntibodyBSA Free [NBP1-76400]

Western Blot: TARBP1 Antibody [NBP1-76400] - 3T3 cell lysate with TRBP1 antibody at (A) 1 and (B) 2 ug/mL.

Applications for TARBP1 Antibody - BSA Free

Application
Recommended Usage

ELISA

1:100-1:2000

Western Blot

1-2 ug/ml
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Peptide affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: TARBP1

The human trans-activation response (TAR) RNA binding protein 1 (TRBP1) was initially identified as a protein that binds to the HIV-1 TAR RNA and activates the long terminal repeat (LTR) expression in the absence and presence of the viral trans-activator Tat. This binding is enhanced by the presence of co-factors such as elongation factor 1alpha (EF-1alpha), polypyrimidine tract-binding protein (PTB), and the chaperonin-like protein stimulator of TAR RNA-binding proteins (SRB). TRBP1 may act to disengage RNA polymerase II from TAR during transcriptional elongation if the RNA polymerase stalls at the TAR during transcriptional elongation.

Alternate Names

EC 2.1.1.-, FLJ30482, TAR (HIV-1) RNA binding protein 1, TAR RNA loop binding protein, TAR RNA-binding protein 1, TAR RNA-binding protein of 185 kDa, tardbp1, TRM3probable methyltransferase TARBP1, TRP-185TAR (HIV) RNA binding protein 1, TRP185TAR (HIV) RNA-binding protein 1

Entrez Gene IDs

6894 (Human)

Gene Symbol

TARBP1

UniProt

Additional TARBP1 Products

Product Documents for TARBP1 Antibody - BSA Free

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for TARBP1 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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