Tau Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-49607

Novus Biologicals, part of Bio-Techne
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NBP2-49607
NBP2-49607-25ul
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Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Tau Antibodies »

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to amino acids: HAPELLKHQLLGDLHQEGPPLKGAGGKERPGSKEEVDEDRDVDESSPQDSPPSKASPAQDGRPPQTAAREATSIPGFPAEGAIPLPVDFLSKVS

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Tau Antibody - BSA Free

Immunohistochemistry-Paraffin: Tau Antibody [NBP2-49607]

Immunohistochemistry-Paraffin: Tau Antibody [NBP2-49607]

Immunohistochemistry-Paraffin: Tau Antibody [NBP2-49607] - Staining in human cerebral cortex and liver tissues using anti-MAPT antibody. Corresponding MAPT RNA-seq data are presented for the same tissues.
Immunohistochemistry-Paraffin: Tau Antibody [NBP2-49607]

Immunohistochemistry-Paraffin: Tau Antibody [NBP2-49607]

Immunohistochemistry-Paraffin: Tau Antibody [NBP2-49607] - Staining of human liver shows low expression as expected.
Immunohistochemistry-Paraffin: Tau Antibody [NBP2-49607]

Immunohistochemistry-Paraffin: Tau Antibody [NBP2-49607]

Immunohistochemistry-Paraffin: Tau Antibody [NBP2-49607] - Staining of human cerebral cortex shows high expression.

Applications for Tau Antibody - BSA Free

Application
Recommended Usage

Immunohistochemistry

1:200 - 1:500

Immunohistochemistry-Paraffin

1:200 - 1:500
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Tau

Tau is a microtubule binding protein that promotes microtubule assembly and stability. Tau is found to be the major component of the paired helical filaments (PHFs) found in the brains of patients with Alzheimer disease (AD) (1,2). Tau is hyperphosphorylated in PHFs, and specific phosphorylation sites have been implicated in the loss of Tau's association with the membrane cortex during AD disease state, including Ser 199/202, Thr 231, and Ser 393/404 (3). Glycogen synthase kinase-3, or GSK-3, phosphorylates Tau on Ser 396 (4).

Long Name

Microtubule-Associated Protein Tau

Alternate Names

MAPT, MSTD, MTBT1, Neurofibrillary tangle protein, PPND

Gene Symbol

MAPT

Additional Tau Products

Product Documents for Tau Antibody - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Tau Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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