Tau tubulin kinase 2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-92476

Novus Biologicals, part of Bio-Techne
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NBP1-92476
NBP1-92476-25ul
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Key Product Details

Species Reactivity

Validated:

Human, Mouse

Cited:

Human, Mouse

Applications

Validated:

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunoprecipitation, Western Blot

Cited:

Immunocytochemistry/ Immunofluorescence, Immunoprecipitation

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Tau tubulin kinase 2 Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: TTEPLDVTKTQTFSVVPNQDKNNEIMKLLTVGTSEISSRDIDPHVEGQIGQVAEMQKNKISKDDDIMSEDLPGHQGDLSTFLHQEGKREKITPRNGELFHCVS

Reactivity Notes

Human reactivity reported in scientific literature (PMID: 24982133). Mouse reactivity reported in scientific literature (PMID: 25599390).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Tau tubulin kinase 2 Antibody

Western Blot: Tau tubulin kinase 2 Antibody [NBP1-92476]

Western Blot: Tau tubulin kinase 2 Antibody [NBP1-92476]

Western Blot: Tau tubulin kinase 2 Antibody [NBP1-92476] - Analysis in control (vector only transfected HEK293T lysate) and TTBK2 over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (3.1 kDa) in mammalian HEK293T cells).
Immunohistochemistry-Paraffin: Tau tubulin kinase 2 Antibody [NBP1-92476]

Immunohistochemistry-Paraffin: Tau tubulin kinase 2 Antibody [NBP1-92476]

Immunohistochemistry-Paraffin: Tau tubulin kinase 2 Antibody [NBP1-92476] - Staining of human testis shows weak to moderate cytoplasmic positivity in cells in seminiferous ducts.
Immunohistochemistry-Paraffin: Tau tubulin kinase 2 Antibody [NBP1-92476]

Immunohistochemistry-Paraffin: Tau tubulin kinase 2 Antibody [NBP1-92476]

Immunohistochemistry-Paraffin: Tau tubulin kinase 2 Antibody [NBP1-92476] - Staining of human Fallopian tube shows strong positivity in cilia in glandular cells.
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Applications for Tau tubulin kinase 2 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:500 - 1:1000

Immunohistochemistry-Paraffin

1:500 - 1:1000

Western Blot

0.04-0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. ICC/IF, IP reactivity reported in (PMID : 24982133).
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Tau tubulin kinase 2

The Tau tubulin kinase 2 gene encodes a serine-threonine kinase that putatively phosphorylates tau and tubulin proteins. Mutations in thisgene cause spinocerebellar ataxia type 11 (SCA11); a neurodegenerative disease characterized by progressive ataxia andatrophy of the cere

Alternate Names

EC 2.7.11, EC 2.7.11.1, KIAA0847tau-tubulin kinase 2, SCA11, spinocerebellar ataxia 11, tau tubulin kinase 2, TTBK

Gene Symbol

TTBK2

Additional Tau tubulin kinase 2 Products

Product Documents for Tau tubulin kinase 2 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Tau tubulin kinase 2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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