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TBX1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-56667

Novus Biologicals, part of Bio-Techne
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NBP2-56667
NBP2-56667-25ul

Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (95%), Rat (95%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Summary for TBX1 Antibody

Immunogen

This antibody was developed against a recombinant protein corresponding to the following amino acid sequence: TFVFEETRFTAVTAYQNHRITQLKIASNPFAKGFRDCDPEDWPRNHRPGALPLMSAFARSRNPVASPTQPSGTEKD

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for TBX1 Antibody

Immunocytochemistry/ Immunofluorescence: TBX1 Antibody [NBP2-56667]

Immunocytochemistry/ Immunofluorescence: TBX1 Antibody [NBP2-56667]

Immunocytochemistry/Immunofluorescence: TBX1 Antibody [NBP2-56667] - Staining of human cell line HEK 293 shows localization to nuclear bodies & cytoplasmic bodies. Antibody staining is shown in green.

Applications for TBX1 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml
Application Notes
ICC/IF Fixation Permeabilization: Use PFA/Triton X-100.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: TBX1

The T-box (TBX) motif is present in a family of genes whose structural features and expression patterns support their involvement in developmental gene regulation. The TBX gene family are largely conserved throughout metazoan evolution, and these genes code for putative transcription factors that share a uniquely defining DNA-binding domain. TBX genes are a family of developmental regulators with more than 20 members recently identified in invertebrates and vertebrates. Mutations in TBX genes are associated with the onset of several human diseases. Our understanding of functional mechanisms of TBX products has come mainly from the prototypical T/Brachyury, which is a transcription activator. The TBX genes constitute a family of transcriptional regulatory genes that are implicated in a variety of developmental processes ranging from the formation of germ layers to the organizational patterning of the central nervous system.

Alternate Names

brachyury, CAFS, CTHM, DGCR, DGS, DORV, T-box 1, T-box 1 transcription factor C, T-box protein 1, T-box transcription factor TBX1, TBX1C, Testis-specific T-box protein, TGA, VCFS

Gene Symbol

TBX1

Additional TBX1 Products

Product Documents for TBX1 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for TBX1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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