TCAP Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-85544

Novus Biologicals, part of Bio-Techne
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NBP1-85544
NBP1-85544-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all TCAP Antibodies »

Product Summary for TCAP Antibody

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: CEVSEENCERREAFWAEWKDLTLSTRPEEGCSLHEEDTQRHETYHQQGQCQVLVQRSPWLMMRMGILGRGLPEYQ

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (89%)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for TCAP Antibody

Western Blot: TCAP Antibody [NBP1-85544]

Western Blot: TCAP Antibody [NBP1-85544]

Western Blot: TCAP Antibody [NBP1-85544] - Analysis in human skeletal muscle tissue.
Immunohistochemistry-Paraffin: TCAP Antibody [NBP1-85544]

Immunohistochemistry-Paraffin: TCAP Antibody [NBP1-85544]

Immunohistochemistry-Paraffin: TCAP Antibody [NBP1-85544] - Staining of human liver shows no positivity in hepatocytes as expected.
Immunohistochemistry-Paraffin: TCAP Antibody [NBP1-85544]

Immunohistochemistry-Paraffin: TCAP Antibody [NBP1-85544]

Immunohistochemistry-Paraffin: TCAP Antibody [NBP1-85544] - Staining of human heart muscle shows distinct cytoplasmic positivity.
View 1 more images

Applications for TCAP Antibody

Application
Recommended Usage

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200

Western Blot

0.04-0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: TCAP

Sarcomere assembly is regulated by the muscle protein titin. Titin is a giant elastic protein with kinase activity that extends half the length of a sarcomere. It serves as a scaffold to which myofibrils and other muscle related proteins are attached. This gene encodes a protein found in striated and cardiac muscle that binds to the titin Z1-Z2 domains and is a substrate of titin kinase, interactions thought to be critical to sarcomere assembly. Mutations in this gene are associated with limb-girdle muscular dystrophy type 2G. [provided by RefSeq]

Alternate Names

19 kDa sarcomeric protein, CMD1NTitin cap protein, LGMD2G, limb girdle muscular dystrophy 2G (autosomal recessive), T-cap, TELE, telethonin, titin-cap (telethonin)

Gene Symbol

TCAP

Additional TCAP Products

Product Documents for TCAP Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for TCAP Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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