TCR alpha Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-45883

Novus Biologicals, part of Bio-Techne
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NBP1-45883-0.025mg
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Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

Immunohistochemistry, Immunoprecipitation, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

0.5 mg/ml

View all TCR alpha Antibodies »

Product Specifications

Immunogen

Synthetic peptide surrounding amino acid 138 of human TCR&alpha.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

This product is manufactured by Abcam and distributed by Novus Biologicals. (Abcam Catalog Number: 5648-100)

Scientific Data Images for TCR alpha Antibody

Western Blot: TCR alpha Antibody [NBP1-45883]

Western Blot: TCR alpha Antibody [NBP1-45883]

Western Blot: TCR alpha Antibody [NBP1-45883] - Analysis of TCRa expression in Jurkat cell lysate.

Applications for TCR alpha Antibody

Application
Recommended Usage

Immunohistochemistry

15 - 25 ug/mL

Immunoprecipitation

10 - 20 ug/mL

Western Blot

0.5 - 4 ug/mL

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.2), 30% glycerol, 0.5% BSA, 5 mM EDTA

Preservative

0.03% Proclin 300

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: TCR alpha

The receptors on T cells consist of immunoglobulin like integral membrane glycoproteins containing 2 polypeptide subunits, alpha and beta, of similar molecular weight, 40 to 55 kD in the human. Like the immunoglobulins of the B cells, each T cell receptor subunit has, external to the cell membrane, an N terminal variable domain and a C terminal constant domain. T cell receptors recognise foreign antigens which have been processed as small peptides and bound to major histocompatibility complex molecules at the surface of antigen presenting cells. Each T cell receptor is a dimer consisting of one alpha and one beta chain or one delta and one gamma chain. In a single cell, the T cell receptor loci are rearranged and expressed in the order delta, gamma, beta, and alpha. If both delta and gamma rearrangements produce functional chains, the cell expresses delta and gamma. If not, the cell proceeds to rearrange the beta and alpha loci.

Alternate Names

C), D, FLJ22602, J, MGC117436, MGC22624, MGC23964, MGC71411, T cell receptor alpha locus, T-cell antigen receptor, alpha polypeptide, T-cell receptor, alpha (V, TCRA, TCRD, TRA

Entrez Gene IDs

6955 (Human)

Gene Symbol

TRA

Additional TCR alpha Products

Product Documents for TCR alpha Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for TCR alpha Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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