TCTN1 Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-77182

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Validated:

Human, Mouse

Applications

ELISA, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1 mg/ml

View all TCTN1 Antibodies »

Product Summary for TCTN1 Antibody - BSA Free

Immunogen

Antibody was raised against a 15 amino acid synthetic peptide near the amino terminus of human TCTN1. The immunogen is located within amino acids 30 - 80 of TCTN1. Amino Acid Squence: PSTRPPGTPRAPGPS

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for TCTN1 Antibody - BSA Free

Western Blot: TCTN1 AntibodyBSA Free [NBP1-77182]

Western Blot: TCTN1 AntibodyBSA Free [NBP1-77182]

Western Blot: TCTN1 Antibody [NBP1-77182] - Mouse kidney tissue lysate with TCTN1 antibody at (A) 1 and (B) 2ug/mL.
Immunocytochemistry/ Immunofluorescence: TCTN1 Antibody - BSA Free [NBP1-77182]

Immunocytochemistry/ Immunofluorescence: TCTN1 Antibody - BSA Free [NBP1-77182]

Immunocytochemistry/Immunofluorescence: TCTN1 Antibody [NBP1-77182] - Human Kidney cells with TCTN1 antibody at 20 ug/mL.
Immunohistochemistry-Paraffin: TCTN1 Antibody - BSA Free [NBP1-77182]

Immunohistochemistry-Paraffin: TCTN1 Antibody - BSA Free [NBP1-77182]

Immunohistochemistry-Paraffin: TCTN1 Antibody [NBP1-77182] - Human kidney tissue with TCTN1 antibody at 5 ug/mL.

Applications for TCTN1 Antibody - BSA Free

Application
Recommended Usage

ELISA

1:100-1:2000

Immunocytochemistry/ Immunofluorescence

20 ug/mL

Immunohistochemistry

5 ug/ml

Immunohistochemistry-Paraffin

5 ug/ml

Western Blot

1-2 ug/ml
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Peptide affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: TCTN1

TCTN1 is the founding member of the Tectonic protein family, a group of evolutionarily conserved secreted and transmembrane proteins that regulate the Hedgehog (Hh)-mediated patterning of the neural tube. During embryonic development, TCTN1 is expressed in regions that participate in Hh signaling, beginning in the gastrulation stages in the ventral node. Mice expressing mutant TCTN1 die between E13.5 and E16.5 and display holoprosencephaly, a defect associated with reduced Hh signaling, indicating the role of TCTN1 as an Hh activator. At later stages in development, TCTN1 is thought to also act as a repressor on the Hh pathway in the anterior and posterior neural tube.

Long Name

Tectonic Family Member 1

Alternate Names

JBTS13, TECT1, Tectonic-1

Gene Symbol

TCTN1

UniProt

NP_001076007 (Human)

Additional TCTN1 Products

Product Documents for TCTN1 Antibody - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for TCTN1 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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