TDP-43/TARDBP Antibody - Azide and BSA Free
Novus Biologicals, part of Bio-Techne | Catalog # NBP2-29648
Key Product Details
Species Reactivity
Human, Rat
Applications
Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Western Blot
Label
Unconjugated
Antibody Source
Polyclonal Rabbit IgG
Format
Azide and BSA Free
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Product Specifications
Immunogen
Synthetic peptide C-terminal to the caspase-cleavage site (between D219 and V220) of human TDP-43. Accession # Q13148. Accession # Q13148
Reactivity Notes
The antibody has been directly tested for reactivity in human and rat.
Specificity
Specific for the ~ 43kDa TDP-43 protein in Western blots of rat brain lysate. Expected molecular weight is dependent upon the TDP-43 species present in sample (full-length vs. truncated TDP-43). Under non-denaturing conditions (for example, by IHC), this antibody detects TDP-43 inclusions in human brain tissue with TDP-43 proteinopathy, but does not detect full-length nuclear TDP-43. Under denaturing conditions (for example, by Western Blot analysis) this antibody detects the C-terminus of full-length and truncated human TDP-43.
Clonality
Polyclonal
Host
Rabbit
Isotype
IgG
Theoretical MW
43 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Description
Recommended that the undiluted antibody be aliquoted into smaller working volumes (10-30 uL/vial depending on usage).
Scientific Data Images for TDP-43/TARDBP Antibody - Azide and BSA Free
Western Blot: TDP-43/TARDBP AntibodyAzide and BSA Free [NBP2-29648]
Western Blot: TARDBP Antibody [NBP2-29648] - neonatal rat brain lysate showing specific immunolabeling of the ~ 43 kDa TDP43 protein.Applications for TDP-43/TARDBP Antibody - Azide and BSA Free
Application
Recommended Usage
Immunocytochemistry/ Immunofluorescence
1:1000
Immunohistochemistry
1:250
Western Blot
1:1000
Formulation, Preparation, and Storage
Purification
Affinity purified
Formulation
PBS and 30% Glycerol
Format
Azide and BSA Free
Preservative
No Preservative
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store at -20C. Avoid freeze-thaw cycles.
Background: TDP-43/TARDBP
Long Name
TAR DNA-binding Protein 43
Alternate Names
ALS10, TARDBP, TDP43
Entrez Gene IDs
23435 (Human)
Gene Symbol
TARDBP
UniProt
Additional TDP-43/TARDBP Products
Product Documents for TDP-43/TARDBP Antibody - Azide and BSA Free
Product Specific Notices for TDP-43/TARDBP Antibody - Azide and BSA Free
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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