Tec Antibody (S09-6E7)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-19784

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
Catalog #
Availability
Size / Price
Qty
NBP3-19784-100ul
NBP3-19784-50ul
Print Quote
Bulk Order
100% Guarantee

Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Applications

Immunocytochemistry/ Immunofluorescence, Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # S09-6E7

Concentration

0.3 mg/ml

View all Tec Antibodies »

Product Summary for Tec Antibody (S09-6E7)

Immunogen

A synthetic peptide of human Tec (Uniprot # P42680)

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Tec Antibody (S09-6E7)

Western Blot: Tec Antibody (S09-6E7) [NBP3-19784]

Western Blot: Tec Antibody (S09-6E7) [NBP3-19784]

Western Blot: Tec Antibody (S09-6E7) [NBP3-19784] - Western blot detection of Tec in K562 cell lysates using NBP3-19784 (1:1000 diluted). Predicted band size: 74kDa. Observed band size: 58-75kDa.
Immunocytochemistry/ Immunofluorescence: Tec Antibody (S09-6E7) [NBP3-19784]

Immunocytochemistry/ Immunofluorescence: Tec Antibody (S09-6E7) [NBP3-19784]

Immunocytochemistry/Immunofluorescence: Tec Antibody (S09-6E7) [NBP3-19784] - Immunocytochemistry of Tec (green) in Hela cells using NBP3-19784 at dilution 1/50, and DAPI (blue)

Applications for Tec Antibody (S09-6E7)

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1/20-1/100

Western Blot

1/2000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.05% BSA

Preservative

0.01% Sodium Azide

Concentration

0.3 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Tec

Tec is a member of the Tec family of non-receptor protein-tyrosine kinase (PTK) which also includes Btk, emtk/itk/Tsk, Rlk/Txx and Bmx (1). Tec is composed of a pleckstrin domain (PH), an SH3 and SH2 domain, a catalytic kinase domain and a Tec homology domain (TH) (2). Tec's TH domain interacts with the SH3 domain of Grb2, Src family PTKs (Fyn, Lyn, and Hck), Vav, and c-Kit. Tec is mostly expressed in hematopoietic cells. Tec's SH3 domain interacts with DC28 and has been shown to phosphorylate p62dok, CD28 substrate (3). Tec can phosphorylate Jak kinase in hematopoietic cells (4) and can also be phosphorylated by Src member Lyn on multiple tyrosine residues (5).

Long Name

Translocated in Extraskeletal Chondrosarcoma Protein Tyrosine Kinase

Alternate Names

PSCTK4

Gene Symbol

TEC

Additional Tec Products

Product Documents for Tec Antibody (S09-6E7)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for Tec Antibody (S09-6E7)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Privacy and Cookie Policy
Site Map
© Copyright 2024 Bio-Techne. All Rights Reserved.