Tef Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-84300

Novus Biologicals, part of Bio-Techne
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NBP2-84300-0.1ml
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit

Concentration

0.5 mg/ml

View all Tef Antibodies »

Product Summary for Tef Antibody

Immunogen

The immunogen is a synthetic peptide directed towards the N-terminal region of human Tef. Peptide sequence: PVDPQAGPGPGPGRAAGERGLSGSFPLVLKKLMENPPREARLDKEKGKEK The peptide sequence for this immunogen was taken from within the described region.

Clonality

Polyclonal

Host

Rabbit

Scientific Data Images for Tef Antibody

Western Blot: Tef Antibody [NBP2-84300]

Western Blot: Tef Antibody [NBP2-84300]

Western Blot: Tef Antibody [NBP2-84300] - WB Suggested Anti-TEF Antibody Titration: 0.2-1 ug/ml. Positive Control: HepG2 cell lysate
Immunohistochemistry: Tef Antibody [NBP2-84300]

Immunohistochemistry: Tef Antibody [NBP2-84300]

Immunohistochemistry: Tef Antibody [NBP2-84300] - Immunohistochemistry with Skeletal muscle tissue at an antibody concentration of 5ug/ml using anti-TEF antibody

Applications for Tef Antibody

Application
Recommended Usage

Western Blot

1.0 ug/ml
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, 2% Sucrose

Preservative

0.09% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Tef

Thyrotroph embryonic factor (TEF), a transcription factor, is a member of the PAR (proline and acidic amino acid-rich) subfamily of basic region/leucine zipper (bZIP) transcription factors. It is expressed in a broad range of cells and tissues in adult animals, however, during embryonic development, TEF expression appears to be restricted to the developing anterior pituitary gland, coincident with the appearance of thyroid-stimulating hormone, beta (TSHB). Indeed, TEF can bind to, and transactivate the TSHB promoter. It shows homology (in the functional domains) with other members of the PAR-bZIP subfamily of transcription factors, which include albumin D box-binding protein (DBP), human hepatic leukemia factor (HLF) and chicken vitellogenin gene-binding protein (VBP); VBP is considered the chicken homologue of TEF. Different members of the subfamily can readily form heterodimers, and share DNA-binding, and transcriptional regulatory properties. Alternatively spliced transcript variants encoding different isoforms have been found for this gene

Alternate Names

KIAA1655thyrotroph embryonic factor, thyrotrophic embryonic factor

Gene Symbol

TEF

Additional Tef Products

Product Documents for Tef Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Tef Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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