TFEB Antibody (S05-0D7)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-14901

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-14901-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunohistochemistry, Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # S05-0D7

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all TFEB Antibodies »

Product Summary for TFEB Antibody (S05-0D7)

Immunogen

Recombinant protein of human TFEB (Uniprot#: P19484)

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for TFEB Antibody (S05-0D7)

Western Blot: TFEB Antibody (S05-0D7) [NBP3-14901]

Western Blot: TFEB Antibody (S05-0D7) [NBP3-14901]

Western Blot: TFEB Antibody (S05-0D7) [NBP3-14901] - Western blot detection of TFEB in A549, HL-60 cell lysates using TFEB Rabbit mAb (1:1000 diluted). Predicted band size: 53kDa. Observed band size: 65-70kDa.
Immunohistochemistry: TFEB Antibody (S05-0D7) [NBP3-14901]

Immunohistochemistry: TFEB Antibody (S05-0D7) [NBP3-14901]

Immunohistochemistry: TFEB Antibody (S05-0D7) [NBP3-14901] - Immunohistochemical of TFEB in Human lung cancer tissue using TFEB antibody at dilution 1/20

Applications for TFEB Antibody (S05-0D7)

Application
Recommended Usage

Immunohistochemistry

1/50

Western Blot

1/1000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.05% BSA

Preservative

0.01% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: TFEB

Transcription factor that specifically recognizes and binds E-box sequences (3'-CANNTG-5'). Efficient DNA-binding requires dimerization with itself or with another MiT/TFE family member such as TFE3 or MITF. In association with TFE3, activates the expression of CD40L in T-cells, thereby playing a role in T-cell-dependent antibody responses in activated CD4(+) T-cells and thymus-dependent humoral immunity. Specifically recognizes and binds the CLEAR-box sequence (5'-GTCACGTGAC-3') present in the regulatory region of many lysosomal genes, leading to activate their expression. It thereby plays a central role in expression of lysosomal genes. Specifically recognizes the gamma-E3 box, a subset of E-boxes, present in the heavy-chain immunoglobulin enhancer. Plays a role in the signal transduction processes required for normal vascularization of the placenta

Long Name

Transcription Factor EB

Alternate Names

ALPHATFEB, BHLHE35, TCFEB

Gene Symbol

TFEB

Additional TFEB Products

Product Documents for TFEB Antibody (S05-0D7)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for TFEB Antibody (S05-0D7)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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