Key Product Details

Species Reactivity

Human

Applications

ELISA, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1 mg/ml

View all TFEB Antibodies »

Product Specifications

Immunogen

Antibody was raised against a 16 amino acid peptide near the carboxy terminus of human TFEB. The immunogen is located within amino acids 390 - 440 of TFEB. Amino Acid Squence: FGGREDEGPPGYPEPL

Specificity

TFEB antibody is human specific. At least three isoforms of TFEB are known to exist.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

53 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for TFEB Antibody - BSA Free

Immunocytochemistry/ Immunofluorescence: TFEB Antibody - BSA Free [NBP2-41168]

Immunocytochemistry/ Immunofluorescence: TFEB Antibody - BSA Free [NBP2-41168]

Immunocytochemistry/Immunofluorescence: TFEB Antibody [NBP2-41168] - Immunofluorescence of TFEB in human lung tissue with TFEB antibody at 20 ug/mL.
Immunohistochemistry-Paraffin: TFEB Antibody - BSA Free [NBP2-41168]

Immunohistochemistry-Paraffin: TFEB Antibody - BSA Free [NBP2-41168]

Immunohistochemistry-Paraffin: TFEB Antibody [NBP2-41168] - Human lung tissue with TFEB antibody at 2.5 ug/mL.
TFEB Antibody - BSA Free

Immunocytochemistry/ Immunofluorescence: TFEB Antibody - BSA Free [NBP2-41168] -

Immunocytochemistry/ Immunofluorescence: TFEB Antibody - BSA Free [NBP2-41168] - Immunofluorescence of TFEB in human lung tissue with TFEB antibody at 20 u/mL.
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Applications for TFEB Antibody - BSA Free

Application
Recommended Usage

ELISA

1:100-1:2000

Immunocytochemistry/ Immunofluorescence

20 ug

Immunohistochemistry

2.5 ug/ml

Immunohistochemistry-Paraffin

2.5 ug/ml

Formulation, Preparation, and Storage

Purification

Peptide affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: TFEB

Transcription factor that specifically recognizes and binds E-box sequences (3'-CANNTG-5'). Efficient DNA-binding requires dimerization with itself or with another MiT/TFE family member such as TFE3 or MITF. In association with TFE3, activates the expression of CD40L in T-cells, thereby playing a role in T-cell-dependent antibody responses in activated CD4(+) T-cells and thymus-dependent humoral immunity. Specifically recognizes and binds the CLEAR-box sequence (5'-GTCACGTGAC-3') present in the regulatory region of many lysosomal genes, leading to activate their expression. It thereby plays a central role in expression of lysosomal genes. Specifically recognizes the gamma-E3 box, a subset of E-boxes, present in the heavy-chain immunoglobulin enhancer. Plays a role in the signal transduction processes required for normal vascularization of the placenta

Long Name

Transcription Factor EB

Alternate Names

ALPHATFEB, BHLHE35, TCFEB

Gene Symbol

TFEB

Additional TFEB Products

Product Documents for TFEB Antibody - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for TFEB Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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